Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …

The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …

Fibroblasts display extensive transcriptional heterogeneity, yet functional annotation and
characterization of their heterocellular relationships remains incomplete. Using mass …

Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …

Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

Abstract As of April 15, 2020, the ongoing coronavirus disease 2019 (COVID-2019)
pandemic has swept through 213 countries and infected more than 1,870,000 individuals …

The development of lipid nanoparticle (LNP) formulations for targeting the bone
microenvironment holds significant potential for nucleic acid therapeutic applications …

Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

There has been an escalation in reports over the last decade examining the efficacy of bone
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …