The secretion profile of mesenchymal stem cells and potential applications in treating human diseases
Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …
Recent updates of diagnosis, pathophysiology, and treatment on osteoarthritis of the knee
S Jang, K Lee, JH Ju - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …
Mesenchymal stem/stromal cells in cancer therapy
T Lan, M Luo, X Wei - Journal of Hematology & Oncology, 2021 - Springer
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …
marrow in 1976, have been identified in nearly all tissues of human body now. The …
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity
C Hutton, F Heider, A Blanco-Gomez, A Banyard… - Cancer cell, 2021 - cell.com
Fibroblasts display extensive transcriptional heterogeneity, yet functional annotation and
characterization of their heterocellular relationships remains incomplete. Using mass …
characterization of their heterocellular relationships remains incomplete. Using mass …
Mesenchymal stem/stromal cell senescence: hallmarks, mechanisms, and combating strategies
Z Weng, Y Wang, T Ouchi, H Liu, X Qiao… - Stem Cells …, 2022 - academic.oup.com
Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …
physiological functions across tissues and organs, leading to overt frailty, mortality, and …
Immune modulation by mesenchymal stem cells
W Jiang, J Xu - Cell proliferation, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …
Current status of potential therapeutic candidates for the COVID-19 crisis
J Zhang, B Xie, K Hashimoto - Brain, behavior, and immunity, 2020 - Elsevier
Abstract As of April 15, 2020, the ongoing coronavirus disease 2019 (COVID-2019)
pandemic has swept through 213 countries and infected more than 1,870,000 individuals …
pandemic has swept through 213 countries and infected more than 1,870,000 individuals …
Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment
L Xue, N Gong, SJ Shepherd, X Xiong… - Journal of the …, 2022 - ACS Publications
The development of lipid nanoparticle (LNP) formulations for targeting the bone
microenvironment holds significant potential for nucleic acid therapeutic applications …
microenvironment holds significant potential for nucleic acid therapeutic applications …
Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
Clinical application of bone marrow mesenchymal stem/stromal cells to repair skeletal tissue
A Arthur, S Gronthos - International journal of molecular sciences, 2020 - mdpi.com
There has been an escalation in reports over the last decade examining the efficacy of bone
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …