Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

BRH Van den Bergh, MI van den Heuvel… - Neuroscience & …, 2020 - Elsevier
Accumulating research shows that prenatal exposure to maternal stress increases the risk
for behavioral and mental health problems later in life. This review systematically analyzes …

Klotho, aging, and the failing kidney

S Buchanan, E Combet, P Stenvinkel… - Frontiers in …, 2020 - frontiersin.org
Klotho has been recognized as a gene involved in the aging process in mammals for over
30 years, where it regulates phosphate homeostasis and the activity of members of the …

Inflammation and premature ageing in chronic kidney disease

T Ebert, SC Pawelzik, A Witasp, S Arefin, S Hobson… - Toxins, 2020 - mdpi.com
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic
phenotype and contribute to impaired health status, reduced quality of life, and premature …

Chronic kidney disease and premature ageing

JP Kooman, P Kotanko, AMWJ Schols… - Nature Reviews …, 2014 - nature.com
Chronic kidney disease (CKD) shares many phenotypic similarities with other chronic
diseases, including heart failure, chronic obstructive pulmonary disease, HIV infection and …

Inflammation and oxidative stress in chronic kidney disease and dialysis patients

T Ebert, O Neytchev, A Witasp… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

Inflammation and premature aging in advanced chronic kidney disease

JP Kooman, MJ Dekker, LA Usvyat… - American Journal …, 2017 - journals.physiology.org
Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …

The signaling of cellular senescence in diabetic nephropathy

Y Xiong, L Zhou - Oxidative Medicine and Cellular Longevity, 2019 - Wiley Online Library
Diabetic nephropathy is the leading cause of chronic kidney disease (CKD) in western
countries. Notably, it has a rapidly rising prevalence in China. The patients, commonly …

Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood

S Entringer, ES Epel, R Kumsta, J Lin… - Proceedings of the …, 2011 - National Acad Sciences
Leukocyte telomere length (LTL) is a predictor of age-related disease onset and mortality.
The association in adults of psychosocial stress or stress biomarkers with LTL suggests …

Gender and telomere length: systematic review and meta-analysis

M Gardner, D Bann, L Wiley, R Cooper, R Hardy… - Experimental …, 2014 - Elsevier
Background It is widely believed that females have longer telomeres than males, although
results from studies have been contradictory. Methods We carried out a systematic review …

Chronic kidney disease: a clinical model of premature aging

P Stenvinkel, TE Larsson - American journal of kidney diseases, 2013 - Elsevier
Premature aging is a process associated with a progressive accumulation of deleterious
changes over time, an impairment of physiologic functions, and an increase in the risk of …