Systematic review of the role of cytoreductive nephrectomy in the targeted therapy era and beyond: an individualized approach to metastatic renal cell carcinoma

B Bhindi, EJ Abel, L Albiges, K Bensalah, SA Boorjian… - European urology, 2019 - Elsevier
Context The role of cytoreductive nephrectomy (CN) in the management of metastatic renal
cell carcinoma (mRCC) in the targeted therapy (TT) era is controversial. Objective To assess …

Individualised indications for cytoreductive nephrectomy: which criteria define the optimal candidates?

A Larcher, CJD Wallis, A Bex, ML Blute… - European Urology …, 2019 - Elsevier
Context The current role of cytoreductive nephrectomy (CN) is controversial. Objective
Review of the available evidence about criteria defining CN optimal candidates. Evidence …

Survival analyses of patients with metastatic renal cancer treated with targeted therapy with or without cytoreductive nephrectomy: a national cancer data base study

N Hanna, M Sun, CP Meyer, PL Nguyen… - Journal of Clinical …, 2016 - ascopubs.org
Purpose The role of cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma
(mRCC) has become unclear since the introduction of targeted therapies (TT). We sought to …

Should CARMENA really change our attitude towards cytoreductive nephrectomy in metastatic renal cell carcinoma? A systematic review and meta-analysis …

F Massari, V Di Nunno, L Gatto, M Santoni… - Targeted Oncology, 2018 - Springer
Background Cytoreductive nephrectomy in metastatic renal cell carcinoma (mRCC) patients
has been common clinical practice due to evidence that resection of the primary tumor …

Nephrectomy improves overall survival in patients with metastatic renal cell carcinoma in cases of favorable MSKCC or ECOG prognostic features

R Mathieu, G Pignot, A Ingles, M Crepel, P Bigot… - … Oncology: seminars and …, 2015 - Elsevier
Objectives The role of cytoreductive nephrectomy (CN) in the treatment of patients harboring
metastatic renal cell carcinoma (mRCC) has become controversial since the emergence of …

Cytoreductive nephrectomy in metastatic renal cell carcinoma treated with targeted therapies: a systematic review with a meta-analysis

F Petrelli, A Coinu, I Vavassori, M Cabiddu… - Clinical genitourinary …, 2016 - Elsevier
Cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma (mRCC)(resection of the
primary tumor for debulking purposes) was considered to be an important part of oncological …

The role of cytoreductive nephrectomy: European Association of Urology recommendations in 2016

A Bex, B Ljungberg, H van Poppel, T Powles… - European urology, 2016 - Elsevier
Patient summary After the introduction of systemic targeted therapies, the use of
nephrectomy in patients with metastatic renal cell carcinoma has declined. Currently …

Clinical correlates and prognostic value of different metastatic sites in metastatic renal cell carcinoma

O Abdel-Rahman - Future Oncology, 2017 - Taylor & Francis
Aim: Real life data on the clinical correlates and prognostic value of metastatic sites in
metastatic renal cell carcinoma (RCC) are needed. This parameter was assessed in RCC …

Prognostic effect of cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma: a comparative study using inverse probability of treatment weighting

T Klatte, K Fife, SJ Welsh, M Sachdeva… - World Journal of …, 2018 - Springer
Purpose To test the hypothesis that cytoreductive nephrectomy (CN) improves overall
survival (OS) of patients with synchronous metastatic renal cell carcinoma (mRCC), who …

The association between cytoreductive nephrectomy and overall survival in metastatic renal cell carcinoma with primary tumor size≤ 4 cm

S Tappero, F Barletta, ML Piccinelli, CC Garcia… - European Urology …, 2023 - Elsevier
Background It is unknown whether the survival benefit of cytoreductive nephrectomy (CN) in
metastatic renal cell carcinoma (mRCC) applies to patients with primary tumor size≤ 4 cm …