Modular pharmacology: deciphering the interacting structural organization of the targeted networks

Z Wang, Y Wang - Drug discovery today, 2013 - Elsevier
Because multiple drugs act within the context of the regulatory networks in which drug
targets and disease gene products function, module-designed studies are becoming …

β2-Adrenergic receptor agonists as a treatment for diabetic kidney disease

E Arif, D Medunjanin, A Solanki, X Zuo… - American Journal …, 2024 - journals.physiology.org
We have previously shown that the long-acting β2-adrenergic receptor (β2-AR) agonist
formoterol induced recovery from acute kidney injury in mice. To determine whether …

Corticosteroid and long‐acting ß‐agonist therapy reduces epithelial goblet cell metaplasia

ME Lachowicz‐Scroggins… - Clinical & …, 2017 - Wiley Online Library
Background Bronchial epithelial goblet cell metaplasia (GCM) with hyperplasia is a
prominent feature of asthma, but the effects of treatment with corticosteroids alone or in …

儿童哮喘控制联合用药的选择

董文芳, 洪建国 - 临床儿科杂志, 2011 - cqvip.com
哮喘是儿童最常见的异质性慢性疾病, 需要长期规律的治疗. 哮喘发病机制复杂,
多种环境因素同时作用, 治疗更是复杂多样. 目前, 除了避免接触可能诱发哮喘的各种变应原和 …

Evaluation of the urinary threshold concentration of formoterol in sports drug testing

R Ventura, LMP Damasceno, R Ramírez… - Drug Testing and …, 2013 - Wiley Online Library
The use of formoterol in sports is allowed by inhalation at the maximum recommended
therapeutic dose. Recently, a threshold concentration of 30 ng. mL‐1 was defined by the …

Akute nongenomische Effekte von Corticosteron auf die Muskarin-induzierte Bronchokonstriktion bei der Maus

D Jachens - 2011 - jlupub.ub.uni-giessen.de
Bei der Maus reagieren die kleinen luftleitenden Atemwege auf Muskarin mit einer
Kontraktion. Muskarin bindet an muskarinische Acetylcholinrezeptoren, die unter …

[图书][B] The pathogenesis of rhinoviral-induced asthma exacerbations

ME Lachowicz-Scroggins - 2010 - search.proquest.com
Rhinoviral infections are the commonest cause of asthma exacerbations. In vitro, the
susceptibility to infection with rhinovirus depends on the degree of differentiation of cultures …