Neurobiology of fibromyalgia and chronic widespread pain

KA Sluka, DJ Clauw - Neuroscience, 2016 - Elsevier
Fibromyalgia is the current term for chronic widespread musculoskeletal pain for which no
alternative cause can be identified. The underlying mechanisms, in both human and animal …

Fibromyalgia: a critical and comprehensive review

AT Borchers, ME Gershwin - Clinical reviews in allergy & immunology, 2015 - Springer
Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise
classification. It is often considered as part of the global overview of functional somatic …

Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome

M Meeus, J Nijs - Clinical rheumatology, 2007 - Springer
In addition to the debilitating fatigue, the majority of patients with chronic fatigue syndrome
(CFS) experience chronic widespread pain. These pain complaints show the greatest …

Central sensitization in tension-type headache—possible pathophysiological mechanisms

L Bendtsen - Cephalalgia, 2000 - journals.sagepub.com
The aim of the present thesis was to investigate the pathophysiology of chronic tension-type
headache with special reference to central mechanisms. Increased tenderness to palpation …

Prescription of exercises for the treatment of chronic pain along the continuum of nociplastic pain: A systematic review with meta‐analysis

K Ferro Moura Franco, D Lenoir… - … Journal of Pain, 2021 - Wiley Online Library
Abstract Background and Objective To compare different exercise prescriptions for patients
with chronic pain along the continuum of nociplastic pain: fibromyalgia, chronic whiplash …

Narrative review: the pathophysiology of fibromyalgia

AM Abeles, MH Pillinger, BM Solitar… - Annals of internal …, 2007 - acpjournals.org
Primary fibromyalgia is a common yet poorly understood syndrome characterized by diffuse
chronic pain accompanied by other somatic symptoms, including poor sleep, fatigue, and …

Generalized hypervigilance in fibromyalgia: evidence of perceptual amplification

AJ McDermid, GB Rollman, GA McCain - PAIN®, 1996 - Elsevier
The hypervigilance model of pain perception states that chronic pain patients have a
heightened sensitivity to pain (eg low threshold and tolerance) because of increased …

Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome

R Staud, RC Cannon, AP Mauderli, ME Robinson… - Pain, 2003 - Elsevier
Individuals diagnosed with fibromyalgia syndrome (FMS) report chronic pain that is
frequently worsened by physical activity and improved by rest. Palpation of muscle and …

Fibromyalgia in women

JM Mountz, LA Bradley, JG Modell… - … : Official Journal of …, 1995 - Wiley Online Library
Objective. To determine if regional cerebral blood flow (rCBF) in the left and right
hemithalami or the left and right heads of the caudate nucleus is abnormal in women with …

Fibromyalgia: from pathophysiology to therapy

T Schmidt-Wilcke, DJ Clauw - Nature Reviews Rheumatology, 2011 - nature.com
Individuals with fibromyalgia generally experience chronic widespread pain, which can be
accompanied by further symptoms including fatigue, sleep disturbances, cognitive …