Malaria is a highly inflammatory and oxidative disease. The production of reactive oxygen
species by host phagocytes is an essential component of the host response to Plasmodium …

Delirium, a prevalent organ dysfunction in critically ill patients, is independently associated
with increased morbidity. This last decade has witnessed an exponential growth in delirium …

Malaria is an infectious disease and a serious public health problem in the world, with 3.3
billion people in endemic areas in 100 countries and about 200 million new cases each …

Cerebral malaria is a lethal complication of malaria infection characterized by central
nervous system dysfunction and is often not effectively treated by antimalarial combination …

Sepsis is recognized as a life-threatening multi-organ dysfunction resulting from a
dysregulated host response to infection. Although the incidence and mortality of sepsis …

It is well established that IFN-γ is required for the development of experimental cerebral
malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the …

Background Cerebral malaria (CM) is a neurological syndrome that includes coma and
seizures following malaria parasite infection. The pathophysiology is not fully understood …

This review focuses on current clinical and immunological aspects of cerebral malaria
induced by Plasmodium falciparum infection. Albeit many issues concerning the …

Background Sepsis-associated encephalopathy (SAE) is an early and common feature of
severe infections. Oxidative stress is one of the mechanisms associated with the …

Cerebral malaria (CM) is the most severe manifestation of Plasmodium falciparum infection
in children and non-immune adults. Previous work has documented a persistent cognitive …