Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Polysaccharide hydrogels: Functionalization, construction and served as scaffold for tissue engineering

Q Yang, J Peng, H Xiao, X Xu, Z Qian - Carbohydrate Polymers, 2022 - Elsevier
Polysaccharide hydrogels have been widely utilized in tissue engineering. They interact with
the organismal environments, modulating the cargos release and realizing of long-term …

A dual‐cross‐linked hydrogel patch for promoting diabetic wound healing

J Liu, M Qu, C Wang, Y Xue, H Huang, Q Chen, W Sun… - Small, 2022 - Wiley Online Library
Diabetic wound treatment faces significant challenges in clinical settings. Alternative
treatment approaches are needed. Continuous bleeding, disordered inflammatory …

Effect of the nano/microscale structure of biomaterial scaffolds on bone regeneration

L Zhu, D Luo, Y Liu - International Journal of Oral Science, 2020 - nature.com
Natural bone is a mineralized biological material, which serves a supportive and protective
framework for the body, stores minerals for metabolism, and produces blood cells nourishing …

[HTML][HTML] Modulating macrophage activities to promote endogenous bone regeneration: Biological mechanisms and engineering approaches

Y Niu, Z Wang, Y Shi, L Dong, C Wang - Bioactive materials, 2021 - Elsevier
A coordinated interaction between osteogenesis and osteoimmune microenvironment is
essential for successful bone healing. In particular, macrophages play a central regulatory …

Strontium functionalized in biomaterials for bone tissue engineering: A prominent role in osteoimmunomodulation

J You, Y Zhang, Y Zhou - Frontiers in Bioengineering and …, 2022 - frontiersin.org
With the development of bone tissue engineering bio-scaffold materials by adding metallic
ions to improve bone healing have been extensively explored in the past decades …

Photothermal-promoted multi-functional dual network polysaccharide hydrogel adhesive for infected and susceptible wound healing

C Chen, P Zhou, C Huang, R Zeng, L Yang, Z Han… - Carbohydrate …, 2021 - Elsevier
A low-cost wound dressing with efficient sterilization and exhibiting long-term antimicrobial
activity is required for the absence of antibiotics, particularly for the wound healing of …

Engineered probiotics biofilm enhances osseointegration via immunoregulation and anti-infection

L Tan, J Fu, F Feng, X Liu, Z Cui, B Li, Y Han… - Science …, 2020 - science.org
Preventing multidrug-resistant bacteria–related infection and simultaneously improving
osseointegration are in great demand for orthopedic implants. However, current strategies …

Immunomodulatory functions of mesenchymal stem cells in tissue engineering

H Li, S Shen, H Fu, Z Wang, X Li, X Sui… - Stem cells …, 2019 - Wiley Online Library
The inflammatory response to chronic injury affects tissue regeneration and has become an
important factor influencing the prognosis of patients. In previous stem cell treatments, it was …

A toll-like receptor agonist mimicking microbial signal to generate tumor-suppressive macrophages

Y Feng, R Mu, Z Wang, P Xing, J Zhang, L Dong… - Nature …, 2019 - nature.com
Switching macrophages from a pro-tumor type to an anti-tumor state is a promising strategy
for cancer immunotherapy. Existing agents, many derived from bacterial components, have …