The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis
L Benetatos, E Hatzimichael, E Londin… - Cellular and molecular …, 2013 - Springer
The mammalian genome is transcribed in a developmentally regulated manner, generating
RNA strands ranging from long to short non-coding RNA (ncRNAs). NcRNAs generated by …
RNA strands ranging from long to short non-coding RNA (ncRNAs). NcRNAs generated by …
[HTML][HTML] Emerging role of microRNAs in lipid metabolism
Z Yang, T Cappello, L Wang - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Abstract microRNAs (miRNAs or miRs) are small non-coding RNAs that are involved in post-
transcriptional regulation of their target genes in a sequence-specific manner. Emerging …
transcriptional regulation of their target genes in a sequence-specific manner. Emerging …
[HTML][HTML] Role of nuclear receptor SHP in metabolism and cancer
Y Zhang, CH Hagedorn, L Wang - … Acta (BBA)-Molecular Basis of Disease, 2011 - Elsevier
Small heterodimer partner (SHP, NR0B2) is a unique member of the nuclear receptor (NR)
superfamily that contains the dimerization and ligand-binding domain found in other family …
superfamily that contains the dimerization and ligand-binding domain found in other family …
NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells
S Galardi, N Mercatelli, MG Farace… - Nucleic acids …, 2011 - academic.oup.com
MicroRNAs (miRNAs) are potent negative regulators of gene expression involved in all
aspects of cell biology. They finely modulate virtually all physiological pathways in …
aspects of cell biology. They finely modulate virtually all physiological pathways in …
Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks
LJ Eichner, V Giguère - Mitochondrion, 2011 - Elsevier
Mitochondrial dysfunction contributes to the etiology of numerous diseases. Consequently,
improving our knowledge of how to modulate mitochondrial activity is of considerable …
improving our knowledge of how to modulate mitochondrial activity is of considerable …
The tumor suppressor roles of miR-433 and miR-127 in gastric cancer
LH Guo, H Li, F Wang, J Yu, JS He - International journal of molecular …, 2013 - mdpi.com
The discovery of microRNAs (miRNAs) provides a new and powerful tool for studying the
mechanism, diagnosis and treatment of human cancers. Currently, the methylation …
mechanism, diagnosis and treatment of human cancers. Currently, the methylation …
miR-127 regulates cell proliferation and senescence by targeting BCL6
J Chen, M Wang, M Guo, Y Xie, YS Cong - PloS one, 2013 - journals.plos.org
Cellular senescence occurs as a response to extracellular and intracellular stresses and
contributes to aging and age-related pathologies. Emerging evidence suggests that cellular …
contributes to aging and age-related pathologies. Emerging evidence suggests that cellular …
Regulation of microRNA expression and function by nuclear receptor signaling
Z Yang, L Wang - Cell & bioscience, 2011 - Springer
MicroRNAs (miRNAs) are small non-coding RNA transcripts that affect various cellular
pathways by serving as regulators of gene expression at the translational and transcriptional …
pathways by serving as regulators of gene expression at the translational and transcriptional …
The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection
Effective recognition of viral components and the subsequent stimulation of the production of
type I interferons (IFNs) is crucial for the induction of host antiviral immunity. The failure of …
type I interferons (IFNs) is crucial for the induction of host antiviral immunity. The failure of …
MicroRNA-433 inhibits liver cancer cell migration by repressing the protein expression and function of cAMP response element-binding protein
Background: Although its expression is altered in several human diseases, the function of
miR-433 is unknown. Results: miR-433 inhibits HCC cell migration by repressing CREB1 …
miR-433 is unknown. Results: miR-433 inhibits HCC cell migration by repressing CREB1 …