Recent advancements, limitations, and future perspectives of the use of personalized medicine in treatment of colon cancer

A Dey, A Mitra, S Pathak, S Prasad… - … in Cancer Research …, 2023 - journals.sagepub.com
Due to the heterogeneity of colon cancer, surgery, chemotherapy, and radiation are
ineffective in all cases. The genomic profile and biomarkers associated with the process are …

Non-canonical programmed cell death in colon cancer

B Pan, B Zheng, C Xing, J Liu - Cancers, 2022 - mdpi.com
Simple Summary Non-canonical PCD is an important player in colon cancer cell suicide. It
influences colon cancer in many ways, such as through tumorigenesis, treatment, and …

Long circulating cancer cell-targeted bionic nanocarriers enable synergistic combinatorial therapy in colon cancer

Y Zheng, W Guo, L Hu, Z Xiao, X Yang… - … Applied Materials & …, 2023 - ACS Publications
Cancer nanomedicine treatment aims to achieve highly specific targeting and localization to
cancer cells. Coating of nanoparticles with cell membranes endows them with homologous …

[HTML][HTML] Combined High—Throughput Proteomics and Random Forest Machine-Learning Approach Differentiates and Classifies Metabolic, Immune, Signaling and …

C Contini, B Manconi, A Olianas, G Guadalupi… - Cells, 2024 - mdpi.com
Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity,
including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra …

NOX4 has the potential to be a biomarker associated with colon cancer ferroptosis and immune infiltration based on bioinformatics analysis

X Yang, Y Yu, Z Wang, P Wu, X Su, Z Wu, J Gan… - Frontiers in …, 2022 - frontiersin.org
Background Colon cancer (CC) is a common tumor, but its pathogenesis is still not well
understood. Competitive endogenous RNA (ceRNA) theory, ferroptosis and tumor immune …

An age stratified analysis of the biomarkers in patients with colorectal cancer

H Yao, C Li, X Tan - Scientific Reports, 2021 - nature.com
Colorectal cancer (CRC), a common malignant tumor of the digestive tract, has a high
incidence and mortality rate. Several recent studies have found that aging is associated with …

Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides

EM Muntjewerff, K Tang, L Lutter… - Acta …, 2021 - Wiley Online Library
Aim A “leaky” gut barrier has been implicated in the initiation and progression of a multitude
of diseases, for example, inflammatory bowel disease (IBD), irritable bowel syndrome and …

RNA‐binding protein RBM38 inhibits colorectal cancer progression by partly and competitively binding to PTEN 3′ UTR with miR‐92a‐3p

B Guan, G Li, B Wan, X Guo, D Huang… - Environmental …, 2021 - Wiley Online Library
RNA‐binding motif protein 38 (RBM38) belongs to the RNA recognition motif family of RNA‐
binding proteins (RBPs). RBM38 was previously identified to suppress tumorigenesis in …

Single-cell transcriptomic analysis of normal and pathological tissues from the same patient uncovers colon cancer progression

R Sun, Y Yang, W Lü, Y Yang, Y Li, Z Liu, D Diao… - Cell & Bioscience, 2023 - Springer
The aim of the present study was to elucidate the evolutionary trajectory of colon cells from
normal colon mucosa, to adenoma, then to carcinoma in the same microenvironment …

[HTML][HTML] Polymeric nanoparticles approach and identification and characterization of novel biomarkers for colon cancer

R Garg, M Gaur, BG Prajapati, G Agrawal… - Results in …, 2023 - Elsevier
The need for novel approaches to the treatment of colon cancer, a common and deadly
disease, is universal. In this compilation, we look at how polymeric nanoparticles (Polymeric …