CYP3A5 polymorphism, amlodipine and hypertension

YP Zhang, XC Zuo, ZJ Huang, JJ Cai, J Wen… - Journal of human …, 2014 - nature.com
As a major cardiovascular risk factor for stroke, coronary artery disease, heart failure and
end-stage renal disease, hypertension affects approximately one billion people and causes …

Global patterns of genetic diversity and signals of natural selection for human ADME genes

J Li, L Zhang, H Zhou, M Stoneking… - Human molecular …, 2011 - academic.oup.com
Genetic polymorphisms in many genes related to drug absorption, distribution, metabolism
and excretion (ADME genes) contribute to the high heterogeneity of drug responses in …

[HTML][HTML] Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on …

B Hou, X Jia, Z Deng, X Liu, H Liu, H Yu, S Liu - Human Genomics, 2020 - Springer
Background Several genome-wide association studies have identified single-nucleotide
polymorphisms (SNPs), such as rs4409766, rs1004467, and rs3824755 in CYP17A1 and …

Association of CYP3A4, CYP3A5 polymorphisms with lung cancer risk in Bangladeshi population

MS Islam, AGM Mostofa, MU Ahmed, MSB Sayeed… - Tumor Biology, 2014 - Springer
The rate of direct smoking, second hand smoking, and smokeless tobacco users as well as
the amount of environmental pollutant like polycyclic aromatic hydrocarons is increasing in …

Glucocorticoid synthesis-related genes: HSD11B1 and HSD11B2 in hypertensive disorders in pregnancy

M Shimodaira, T Nakayama, I Sato, N Sato… - Gynecological …, 2013 - Taylor & Francis
Objective: To determine whether polymorphisms of the maternal glucocorticoid-related
genes (HSD11B1 and HSD11B2) are associated with pregnancy-induced hypertension …

[HTML][HTML] Association of the CYP3A5 polymorphism (6986G> A) with blood pressure and hypertension

B Xi, C Wang, L Liu, T Zeng, Y Liang, J Li… - Hypertension Research, 2011 - nature.com
The cytochrome P450 family 3 subfamily A polypeptide 5 (CYP3A5) gene has been
implicated in the regulation of blood pressure (BP) and thus, may serve as a potential risk …

Genética y genómica de la hipertensión arterial: una actualización

J Ramírez-Bello, O Pérez-Méndez… - … de cardiología de …, 2011 - scielo.org.mx
La hipertensión arterial es considerada la principal causa de riesgo para el desarrollo de
infarto agudo al miocardio, falla cardiaca, arritmia ventricular, nefropatía, ceguera, entre …

[PDF][PDF] Frequency of the most common CYP3A5 polymorphisms in the healthy population of the Republic of Macedonia

K Jakovski, A Kapedanovska-Nestorovska… - Maced. Pharm …, 2012 - bulletin.mfd.org.mk
The genetic polymorphism affecting the CYP3A5 enzyme is responsible for inter-individual
and interethnic variability in the metabolism of CYP3A5 substrates. The aim of this study was …

Top three pharmacogenomics and personalized medicine applications at the nexus of renal pathophysiology and cardiovascular medicine

M Bochud, M Burnier, I Guessous - … and Personalized Medicine …, 2011 - ingentaconnect.com
Pharmacogenomics is a field with origins in the study of monogenic variations in drug
metabolism in the 1950s. Perhaps because of these historical underpinnings, there has …

Genetic and genomic studies in the hypertension: an actualization

J Ramírez-Bello, O Pérez-Méndez… - … de cardiología de …, 2011 - scielo.org.mx
Genetic and genomic studies in the hypertension: an actualization SciELO - Scientific Electronic
Library Online vol.81 número3 Complicaciones hemorrágicas del tratamiento de los síndromes …