[HTML][HTML] Impact of SARS-CoV-2 pandemic on patients with primary immunodeficiency
S Delavari, H Abolhassani, F Abolnezhadian… - Journal of clinical …, 2021 - Springer
Although it is estimated that COVID-19 life-threatening conditions may be diagnosed in less
than 1: 1000 infected individuals below the age of 50, but the real impact of this pandemic …
than 1: 1000 infected individuals below the age of 50, but the real impact of this pandemic …
Organ‐based clues for diagnosis of inborn errors of immunity: A practical guide for clinicians
Inborn errors of immunity (IEI) comprise a group of about 490 genetic disorders that lead to
aberrant functioning or the development of distinct immune system components. So far, a …
aberrant functioning or the development of distinct immune system components. So far, a …
[HTML][HTML] X-linked TLR7 deficiency underlies critical COVID-19 pneumonia in a male patient with ataxia-telangiectasia
H Abolhassani, A Vosughimotlagh, T Asano… - Journal of clinical …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) exhibits a wide spectrum of
clinical manifestations, ranging from asymptomatic to critical conditions. Understanding the …
clinical manifestations, ranging from asymptomatic to critical conditions. Understanding the …
[HTML][HTML] Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …
[HTML][HTML] Consensus Middle East and North Africa Registry on inborn errors of immunity
Background Inborn errors of immunity (IEIs) are a heterogeneous group of genetic defects of
immunity, which cause high rates of morbidity and mortality mainly among children due to …
immunity, which cause high rates of morbidity and mortality mainly among children due to …
[HTML][HTML] Leukocytoclastic vasculitis in patients with IL12B or IL12RB1 deficiency: case report and review of the literature
N Sharifinejad, SA Mahdaviani, M Jamee… - Pediatric …, 2021 - Springer
Background Mendelian susceptibility to mycobacterial disease (MSMD) is an inborn error of
immunity, resulting in susceptibility to weakly virulent mycobacteria and other …
immunity, resulting in susceptibility to weakly virulent mycobacteria and other …
Effect of class switch recombination defect on the phenotype of ataxia-telangiectasia patients
ABSTRACT Objectives: Ataxia-telangiectasia (AT) is an autosomal recessive
neurodegenerative disorder with multisystem involvement caused by homozygous or …
neurodegenerative disorder with multisystem involvement caused by homozygous or …
Variable abnormalities in T and B cell subsets in ataxia telangiectasia
Background Ataxia-telangiectasia (AT) is a rare genetic condition, caused by biallelic
deleterious variants in the ATM gene, and has variable immunological abnormalities. This …
deleterious variants in the ATM gene, and has variable immunological abnormalities. This …
Evaluation of the frequency and diagnostic delay of primary immunodeficiency disorders among suspected patients based on the 10 warning sign criteria: A cross …
Introduction The prevalence of undiagnosed primary immunodeficiency diseases is
remarkably high and contributes to increasing the rate of morbidity and mortality among this …
remarkably high and contributes to increasing the rate of morbidity and mortality among this …
Genetic mutations and immunological features of severe combined immunodeficiency patients in Iran
Background Severe combined immunodeficiency (SCID) is the most severe form of primary
immunodeficiency disorders that is characterized by impaired early T lymphocyte …
immunodeficiency disorders that is characterized by impaired early T lymphocyte …