Principles of nanoparticle formation by flash nanoprecipitation
WS Saad, RK Prud'homme - Nano Today, 2016 - Elsevier
Rapid precipitation is an efficient approach for engineering materials at the nanoscale. By
controlling solute nucleation and growth rates in solvent precipitation processes, the size of …
controlling solute nucleation and growth rates in solvent precipitation processes, the size of …
Control of polymeric nanoparticle size to improve therapeutic delivery
As nanoparticle (NP)-mediated drug delivery research continues to expand, understanding
parameters that govern NP interactions with the biological environment becomes …
parameters that govern NP interactions with the biological environment becomes …
Current developments and applications of microfluidic technology toward clinical translation of nanomedicines
Nanoparticulate drug delivery systems hold great potential for the therapy of many diseases,
especially cancer. However, the translation of nanoparticulate drug delivery systems from …
especially cancer. However, the translation of nanoparticulate drug delivery systems from …
Crosslinked self-assembled nanoparticles for chemo-sonodynamic combination therapy favoring antitumor, antimetastasis management and immune responses
M Liu, AR Khan, J Ji, G Lin, X Zhao, G Zhai - Journal of Controlled Release, 2018 - Elsevier
Sonodynamic therapy (SDT) has been proposed as a new modality for cancer management
through low-intensity ultrasound induced activation of sonosensitizers. Here, we designed a …
through low-intensity ultrasound induced activation of sonosensitizers. Here, we designed a …
Designing polymers with sugar-based advantages for bioactive delivery applications
Y Zhang, JW Chan, A Moretti, KE Uhrich - Journal of Controlled Release, 2015 - Elsevier
Sugar-based polymers have been extensively explored as a means to increase drug
delivery systems' biocompatibility and biodegradation. Here, we review the use of sugar …
delivery systems' biocompatibility and biodegradation. Here, we review the use of sugar …
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy
M Song, W Xia, Z Tao, B Zhu, W Zhang, C Liu… - Drug Delivery, 2021 - Taylor & Francis
Malignant melanoma is a life-threatening form of skin cancer with a low response rate to
single-agent chemotherapy. Although combined therapies of metformin (MET) and …
single-agent chemotherapy. Although combined therapies of metformin (MET) and …
Flash technology-based self-assembly in nanoformulation: Fabrication to biomedical applications
Advances in nanoformulation have driven progress in biomedicine by producing nanoscale
tools for biosensing, imaging, and drug delivery. Flash-based technology, the combination of …
tools for biosensing, imaging, and drug delivery. Flash-based technology, the combination of …
Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo
Atherosclerosis, the build-up of occlusive, lipid-rich plaques in arterial walls, is a focal trigger
of chronic coronary, intracranial, and peripheral arterial diseases, which together account for …
of chronic coronary, intracranial, and peripheral arterial diseases, which together account for …
Nanomedicine-based strategies for treatment of atherosclerosis
M Schiener, M Hossann, JR Viola… - Trends in molecular …, 2014 - cell.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall that arises from an
imbalanced lipid metabolism and a maladaptive inflammatory response. Despite intensive …
imbalanced lipid metabolism and a maladaptive inflammatory response. Despite intensive …
Sugar-based amphiphilic polymers for biomedical applications: from nanocarriers to therapeutics
L Gu, A Faig, D Abdelhamid… - Accounts of chemical …, 2014 - ACS Publications
Conspectus Various therapeutics exhibit unfavorable physicochemical properties or stability
issues that reduce their in vivo efficacy. Therefore, carriers able to overcome such …
issues that reduce their in vivo efficacy. Therefore, carriers able to overcome such …