Ankylosing spondylitis (AS) is a chronic inflammatory disorder of unknown aetiology. Unlike
other systemic autoimmune diseases, in AS, the innate immune system has a dominant role …

Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …

Entheses are the insertion sites of tendons and ligaments to the bone surface and are
essential structures for locomotion. Inflammation of the entheses (enthesitis) is a key feature …

The term axial spondyloarthritis covers both patients with non-radiographic and radiographic
axial spondyloarthritis, which is also termed ankylosing spondylitis. The disease usually …

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting 3% of the
world's population, and approximately one-third of patients with psoriasis will eventually …

Tendinopathy is a multifactorial spectrum of tendon disorders that affects different
anatomical sites and is characterized by activity-related tendon pain. These disorders are …

Over the past 5 years, advances in high-throughput techniques and studies involving large
cohorts of patients have led to considerable advances in the identification of novel genetic …

Psoriatic arthritis (PsA) is part of a group of closely related clinical phenotypes ('psoriatic
disease') that is defined by shared molecular pathogenesis resulting in excessive …

Axial spondyloarthritis (axSpA) is an inflammatory disease of the axial skeleton associated
with significant pain and disability. Previously, the diagnosis of ankylosing spondylitis …

Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that …