Structure-activity relationships of new Organotin (IV) anticancer agents and their cytotoxicity profile on HL-60, MCF-7 and HeLa human cancer cell lines

H Ullah, V Previtali, HB Mihigo, B Twamley… - European Journal of …, 2019 - Elsevier
There is a growing interest in the cancer cell growth inhibitory effects of organotin (IV)
compounds and, accordingly, a new series of dimethyl-, di-(n-butyl)-, diphenyl-and chloro …

Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties

M Vilková, M Hudáčová, N Palušeková… - Molecules, 2022 - mdpi.com
A series of novel acridine N-acylhydrazone derivatives have been synthesized as potential
topoisomerase I/II inhibitors, and their binding (calf thymus DNA—ctDNA and human serum …

Synthesis of functional (thia) calix [4] arene derivatives using modular azide-alkyne cycloaddition approach

E Makarov, Z Iskhakova, V Burilov, S Solovieva… - Journal of Inclusion …, 2023 - Springer
Today, the modification of the organic molecules using the copper-catalyzed azide-alkyne
cycloaddition reaction (CuAAC) is of great interest, as evidenced by the Nobel Prize in …

Binding of tetrabutylammonium bromide based deep eutectic solvent to DNA by spectroscopic analysis

R Yusof, K Jumbri, H Ahmad, E Abdulmalek… - … Acta Part A: Molecular …, 2021 - Elsevier
The binding characteristics of DNA in deep eutectic solvents (DESs), particularly the binding
energy and interaction mechanism, are not widely known. In this study, the binding of …

Homo-and heteroleptic Zinc (II) carboxylates: Synthesis, structural characterization, and assessment of their biological significance in in vitro models

S Naz, N Uddin, K Ullah, A Haider, A Gul, S Faisal… - Inorganica Chimica …, 2020 - Elsevier
A series of five new zinc (II) complexes of 2-phenylbutyric acid comprising of one homoleptic
(1) and four heteroleptic (2–5) complexes were synthesized under open beaker conditions …

Copper-tolfenamic acid: Evaluation of stability and anti-cancer activity

M Hurtado, UT Sankpal, J Chhabra, DT Brown… - Investigational new …, 2019 - Springer
The non-steroidal anti-inflammatory drug, Tolfenamic acid (TA) acts as an anti-cancer agent
in several adult and pediatric cancer models. Copper (Cu) is an important element with …

Ct-DNA binding and antimicrobial studies of MnII and FeII macrocyclic complexes

A Kumar, VK Vashistha, DK Das, RK Gupta… - Journal of Inclusion …, 2022 - Springer
The designing of efficient macrocyclic complexes for the alteration in nucleic acids and
understanding is still in debate. Herein, to study the deoxyribonucleic acid (DNA) interaction …

Synthesis, characterization and DNA-intercalation studies of two ferrocene-based Fe-Sn heterobimetallic compounds, and crystal structure of trimethyltin (p-ferrocenyl) …

AA Altaf, N Khan, B Lal, A Badshah - Journal of Coordination …, 2017 - Taylor & Francis
In this article, we report the synthesis of two (A3 and A4) new ferrocene-based
heterobimetallic compounds of Fe and Sn. Both compounds are structural isomers with …

[PDF][PDF] Anti-cancer and Anti-oxidant Potencies of Cuscuta reflexa Roxb. Plant Extracts

I Ali, M Suhail, M Fazil, B Ahmad, A Sayeed… - Am. J. Adv. Drug …, 2019 - academia.edu
All around the world, the percentage of deaths due to cancer is continuously increasing-the
greatest devastation of deaths. Among all medications, Unani medicines are boon for …

Docking assisted DNA-binding, biological screening, and nuclease activity of copper complexes derived from sulfonamides

A Akhtar, M Danish, A Asif, MN Arshad… - Journal of Coordination …, 2021 - Taylor & Francis
Copper (II) complexes of sulfonamides have found importance in biological and
pharmaceutical systems. This study focuses on copper (II) complexes that were synthesized …