The first consensus guidelines for scoring the histopathological growth patterns (HGPs) of
liver metastases were established in 2017. Since then, numerous studies have applied …

Colorectal carcinoma is a leading cause of cancer‐related death worldwide. There is
significant prognostic heterogeneity in stages II and III tumours, necessitating the …

Importance Personalized treatment approaches for patients with oligometastatic colorectal
liver metastases are critically needed. We previously defined 3 biologically distinct …

Background The histopathological growth pattern (HGP) of colorectal liver metastases
(CLM) has been associated with prognosis. This study was designed to elucidate if the HGP …

Background Finding a noninvasive radiomic surrogate of tumor immune features could help
identify patients more likely to respond to novel immune checkpoint inhibitors. Particularly …

Background After resection, colorectal cancer liver metastases (CRLM) surrounded by a
desmoplastic rim carry a better prognosis than the metastases replacing the adjacent liver …

Strong immune responses in primary colorectal cancer correspond with better patient
survival following surgery compared with tumors with predominantly stromal …

There is a pressing need for novel immunotherapeutic targets in colorectal cancer (CRC).
Cytotoxic T cell infiltration is well established as a key prognostic indicator in CRC, and it is …

Colorectal cancer (CRC) is a major cause of cancer-related deaths globally. While treatment
advancements have improved survival rates, primarily through targeted therapies based on …

The radiomic analysis of the tissue surrounding colorectal liver metastases (CRLM)
enhances the prediction accuracy of pathology data and survival. We explored the variation …