Following the development of microfluidic systems, there has been a high tendency towards
developing lab-on-a-chip devices for biochemical applications. A great deal of effort has …

Dried blood spots (DBS) typically consist in the deposition of small volumes of capillary
blood onto dedicated paper cards. Comparatively to whole blood or plasma samples, their …

Thiamine is an essential micronutrient that plays a key role in energy metabolism. Many
populations worldwide may be at risk of clinical or subclinical thiamine deficiencies, due to …

Inborn errors of metabolism (IEM) are a phenotypically and genetically heterogeneous
group of disorders caused by a defect in a metabolic pathway, leading to malfunctioning …

This literature review highlights recent advances and challenges in applying dried blood
spots (DBS) as a cumulative technique for sample acquisition, transport, archiving, and …

Digital microfluidics (DMF) has recently emerged as a popular technology for a wide range
of applications. In DMF, nanoliter to microliter droplets containing samples and reagents can …

Molecular diagnostics is crucial for prevention, identification, and treatment of disease.
Traditional technologies for molecular diagnostics using blood are limited to laboratory use …

We present a programmable droplet-based microfluidic device that combines the
reconfigurable flow-routing capabilities of integrated microvalve technology with the sample …

We introduce DropBot: an open-source instrument for digital microfluidics
(http://microfluidics. utoronto. ca/dropbot). DropBot features two key functionalities for digital …

We introduce a new format for particle-based immunoassays relying on digital microfluidics
(DMF) and magnetic forces to separate and resuspend antibody-coated paramagnetic …