[HTML][HTML] IL-27 alters inflammatory cytokine expression and limits protective immunity against Mycobacterium tuberculosis in a neonatal BCG vaccination model

SD Bradford, KJ Ryan, AM Divens… - Frontiers in …, 2024 - frontiersin.org
Background Efforts to control tuberculosis (TB), caused by the pathogen Mycobacterium
tuberculosis (Mtb), have been hampered by the immense variability in protection from BCG …

Monocarboxylate transporter 4 facilitates Mycobacterium tuberculosis survival through NF-κB p65-mediated interleukin-10 production

Y Huang, R Li, S Chen, Q Wang, Z Han, Y Liang… - Iscience, 2024 - cell.com
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(Mtb) infection, with the highest single-cause mortality. Monocarboxylate transporter 4 (Mct4) …

Bacillus Calmette–Guérin–induced interleukin‐10 inhibits S100A8/A9 production and hinders development of T helper type 1 memory in mice

Y Wang, Y Sun, Y Zheng, Y Yang, L He… - European Journal of …, 2023 - Wiley Online Library
Tuberculosis caused by Mycobacterium tuberculosis (M. tb) is one of the main causes of
human death in the world. Bacillus Calmette‐Guérin (BCG) provides limited protection in …

[PDF][PDF] Percentage and Absolute CD4+ Count and Factors Influencing Their Levels in Tuberculosis Patients in a Tertiary Hospital, Kaduna, Nigeria

M Suzie, Y Mohammed, BJ Monday… - … Research & Reports …, 2023 - researchgate.net
Background: The role of CD4+ T cells in immunity against tuberculosis have been widely
acknowledged. This study determined CD4+ absolute, CD4 percentage and haemoglobin …

Investigação de vias apoptóticas em células mononucleares humanas induzidas por diferentes cepas vacinais de Mycobacterium bovis BCG

PRC Sousa - 2023 - repositorio.ufc.br
RESUMO A tuberculose (TB) é considerada a principal causa de morte devida a um único
agente infeccioso. E a BCG é a única vacina licenciada contra a TB, mas que possui …

Avaliação in vitro do padrão de morte celular e níveis de citocinas por diferentes cepas da vacina BCG em células mononucleares humanas

ASM Silva - 2022 - arca.fiocruz.br
A tuberculose (TB) é a segunda doença infecciosa que mais mata no mundo e sua alta
disseminação em países vulneráveis socialmente representa uma preocupação mundial. A …