Thrombus structural composition in cardiovascular disease

G Alkarithi, C Duval, Y Shi, FL Macrae… - … , and vascular biology, 2021 - Am Heart Assoc
Thrombosis is a major complication of cardiovascular disease, leading to myocardial
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

MA Petersen, JK Ryu, K Akassoglou - Nature Reviews Neuroscience, 2018 - nature.com
The blood coagulation protein fibrinogen is deposited in the brain in a wide range of
neurological diseases and traumatic injuries with blood–brain barrier (BBB) disruption …

Fibrinogen and fibrin in hemostasis and thrombosis

S Kattula, JR Byrnes, AS Wolberg - … , thrombosis, and vascular …, 2017 - Am Heart Assoc
Multiple mechanisms mediate thrombin generation and consequently the thrombin
concentration present during fibrin formation. First, the levels of pro-and anticoagulants …

Precision navigation of venous thrombosis guided by viscosity-activatable near-infrared fluorescence

W Zhang, M Li, X Wang, W Zhang, H Wang… - Analytical …, 2023 - ACS Publications
Thrombus are blood clots formed by abnormal hemostasis in blood vessels and are closely
associated with various diseases such as pulmonary embolism, myocardial infarction and …

[HTML][HTML] Embolic strokes of unknown source and cryptogenic stroke: implications in clinical practice

A Nouh, M Hussain, T Mehta, S Yaghi - Frontiers in neurology, 2016 - frontiersin.org
Up to a third of strokes are rendered cryptogenic or of undetermined etiology. This number is
specifically higher in younger patients. At times, inadequate diagnostic workups, multiple …

Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography

PC Naha, KC Lau, JC Hsu, M Hajfathalian, S Mian… - Nanoscale, 2016 - pubs.rsc.org
Earlier detection of breast cancer reduces mortality from this disease. As a result, the
development of better screening techniques is a topic of intense interest. Contrast-enhanced …

[HTML][HTML] Visualizing thrombosis to improve thrombus resolution

JW Weisel, RI Litvinov - Research and practice in thrombosis and …, 2021 - Elsevier
The severity, course, and outcomes of thrombosis are determined mainly by the size and
location of the thrombus, but studying thrombus structure and composition has been an …

Activatable magnetic resonance nanosensor as a potential imaging agent for detecting and discriminating thrombosis

HT Ta, N Arndt, Y Wu, HJ Lim, S Landeen, R Zhang… - Nanoscale, 2018 - pubs.rsc.org
The early detection and accurate characterization of life-threatening diseases such as
cardiovascular disease and cancer are critical to the design of treatment. Knowing whether …

[HTML][HTML] Multimodality advanced cardiovascular and molecular imaging for early detection and monitoring of cancer therapy-associated cardiotoxicity and the role of …

JM Kwan, EK Oikonomou, ML Henry… - Frontiers in …, 2022 - frontiersin.org
Cancer mortality has improved due to earlier detection via screening, as well as due to novel
cancer therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitions …

Molecular imaging of atherothrombotic diseases: seeing is believing

X Wang, K Peter - Arteriosclerosis, thrombosis, and vascular …, 2017 - Am Heart Assoc
Molecular imaging, with major advances in the development of both innovative targeted
contrast agents/particles and radiotracers, as well as various imaging technologies, is a …