Ten things you should know about transposable elements
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …
extent of their impact on genome evolution, function, and disease remain a matter of intense …
Computational tools to unmask transposable elements
P Goerner-Potvin, G Bourque - Nature Reviews Genetics, 2018 - nature.com
A substantial proportion of the genome of many species is derived from transposable
elements (TEs). Moreover, through various self-copying mechanisms, TEs continue to …
elements (TEs). Moreover, through various self-copying mechanisms, TEs continue to …
Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster
A Grandchamp, L Kühl, M Lebherz… - Genome …, 2023 - genome.cshlp.org
Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …
closely related species. Recently, multiple studies across many taxa showed that some …
Latest advances for the sleeping beauty transposon system: 23 years of insomnia but prettier than ever: refinement and recent innovations of the sleeping beauty …
M Amberger, Z Ivics - Bioessays, 2020 - Wiley Online Library
Abstract The Sleeping Beauty transposon system is a nonviral DNA transfer tool capable of
efficiently mediating transposition‐based, stable integration of DNA sequences of choice …
efficiently mediating transposition‐based, stable integration of DNA sequences of choice …
Sex and the TEs: transposable elements in sexual development and function in animals
Transposable elements are endogenous DNA sequences able to integrate into and multiply
within genomes. They constitute a major source of genetic innovations, as they can not only …
within genomes. They constitute a major source of genetic innovations, as they can not only …
Retrotransposons as drivers of mammalian brain evolution
Retrotransposons, a large and diverse class of transposable elements that are still active in
humans, represent a remarkable force of genomic innovation underlying mammalian …
humans, represent a remarkable force of genomic innovation underlying mammalian …
The depths of virus exaptation
EV Koonin, M Krupovic - Current Opinion in Virology, 2018 - Elsevier
Highlights•Viruses and their components are repeatedly exapted for diverse host
functions.•Virus components are often exapted to function in antiviral defense.•Defective …
functions.•Virus components are often exapted to function in antiviral defense.•Defective …
The structural, functional and evolutionary impact of transposable elements in eukaryotes
Transposable elements (TEs) are nearly ubiquitous in eukaryotes. The increase in genomic
data, as well as progress in genome annotation and molecular biology techniques, have …
data, as well as progress in genome annotation and molecular biology techniques, have …
Transposable elements and their role in aging
E Yushkova, A Moskalev - Ageing Research Reviews, 2023 - Elsevier
Transposable elements (TEs) are an important part of eukaryotic genomes. The role of
somatic transposition in aging, carcinogenesis, and other age-related diseases has been …
somatic transposition in aging, carcinogenesis, and other age-related diseases has been …
The role of transposable elements of the human genome in neuronal function and pathology
E Chesnokova, A Beletskiy, P Kolosov - International Journal of …, 2022 - mdpi.com
Transposable elements (TEs) have been extensively studied for decades. In recent years,
the introduction of whole-genome and whole-transcriptome approaches, as well as single …
the introduction of whole-genome and whole-transcriptome approaches, as well as single …