Ten things you should know about transposable elements

G Bourque, KH Burns, M Gehring, V Gorbunova… - Genome biology, 2018 - Springer
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

Computational tools to unmask transposable elements

P Goerner-Potvin, G Bourque - Nature Reviews Genetics, 2018 - nature.com
A substantial proportion of the genome of many species is derived from transposable
elements (TEs). Moreover, through various self-copying mechanisms, TEs continue to …

Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster

A Grandchamp, L Kühl, M Lebherz… - Genome …, 2023 - genome.cshlp.org
Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …

Latest advances for the sleeping beauty transposon system: 23 years of insomnia but prettier than ever: refinement and recent innovations of the sleeping beauty …

M Amberger, Z Ivics - Bioessays, 2020 - Wiley Online Library
Abstract The Sleeping Beauty transposon system is a nonviral DNA transfer tool capable of
efficiently mediating transposition‐based, stable integration of DNA sequences of choice …

Sex and the TEs: transposable elements in sexual development and function in animals

C Dechaud, JN Volff, M Schartl, M Naville - Mobile DNA, 2019 - Springer
Transposable elements are endogenous DNA sequences able to integrate into and multiply
within genomes. They constitute a major source of genetic innovations, as they can not only …

Retrotransposons as drivers of mammalian brain evolution

R Ferrari, N Grandi, E Tramontano, G Dieci - Life, 2021 - mdpi.com
Retrotransposons, a large and diverse class of transposable elements that are still active in
humans, represent a remarkable force of genomic innovation underlying mammalian …

The depths of virus exaptation

EV Koonin, M Krupovic - Current Opinion in Virology, 2018 - Elsevier
Highlights•Viruses and their components are repeatedly exapted for diverse host
functions.•Virus components are often exapted to function in antiviral defense.•Defective …

The structural, functional and evolutionary impact of transposable elements in eukaryotes

D Almojil, Y Bourgeois, M Falis, I Hariyani, J Wilcox… - Genes, 2021 - mdpi.com
Transposable elements (TEs) are nearly ubiquitous in eukaryotes. The increase in genomic
data, as well as progress in genome annotation and molecular biology techniques, have …

Transposable elements and their role in aging

E Yushkova, A Moskalev - Ageing Research Reviews, 2023 - Elsevier
Transposable elements (TEs) are an important part of eukaryotic genomes. The role of
somatic transposition in aging, carcinogenesis, and other age-related diseases has been …

The role of transposable elements of the human genome in neuronal function and pathology

E Chesnokova, A Beletskiy, P Kolosov - International Journal of …, 2022 - mdpi.com
Transposable elements (TEs) have been extensively studied for decades. In recent years,
the introduction of whole-genome and whole-transcriptome approaches, as well as single …