Major depressive disorder and bipolar disorder predispose youth to accelerated atherosclerosis and early cardiovascular disease: a scientific statement from the …

BI Goldstein, MR Carnethon, KA Matthews… - Circulation, 2015 - Am Heart Assoc
In the 2011 “Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk
Reduction in Children and Adolescents,” several medical conditions among youth were …

The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment

A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

Bipolar disorder diagnosis: challenges and future directions

ML Phillips, DJ Kupfer - The Lancet, 2013 - thelancet.com
Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …

Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors

M Berk, F Kapczinski, AC Andreazza, OM Dean… - … & biobehavioral reviews, 2011 - Elsevier
There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

[HTML][HTML] Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

M Khoubnasabjafari, K Ansarin, A Jouyban - BioImpacts: BI, 2015 - ncbi.nlm.nih.gov
Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Potential mechanisms of action of lithium in bipolar disorder: Current understanding

GS Malhi, M Tanious, P Das, CM Coulston, M Berk - CNS drugs, 2013 - Springer
Lithium has been used for over half a century for the treatment of bipolar disorder as the
archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in …

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

JW Gawryluk, JF Wang, AC Andreazza… - International Journal …, 2011 - academic.oup.com
Accruing data suggest that oxidative stress may be a factor underlying the pathophysiology
of bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ) …

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

F Ng, M Berk, O Dean, AI Bush - International Journal of …, 2008 - academic.oup.com
Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …

[HTML][HTML] Emerging roles of brain metabolism in cognitive impairment and neuropsychiatric disorders

IM Morella, R Brambilla, L Morè - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Here we discuss the role of diverse environmental manipulations affecting cognition with
special regard to psychiatric conditions. We present evidence supporting a direct causal …

Biological hypotheses and biomarkers of bipolar disorder

E Sigitova, Z Fišar, J Hroudová… - Psychiatry and …, 2017 - Wiley Online Library
The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …