The clinical use of indocyanine green as a near‐infrared fluorescent contrast agent for image‐guided oncologic surgery

BE Schaafsma, JSD Mieog, M Hutteman… - Journal of surgical …, 2011 - Wiley Online Library
Optical imaging using near‐infrared (NIR) fluorescence provides new prospects for general
and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer‐related surgery …

Spatial frequency domain imaging in 2019: principles, applications, and perspectives

S Gioux, A Mazhar, DJ Cuccia - Journal of biomedical optics, 2019 - spiedigitallibrary.org
Spatial frequency domain imaging (SFDI) has witnessed very rapid growth over the last
decade, owing to its unique capabilities for imaging optical properties and chromophores …

Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation

S Gioux, HS Choi, JV Frangioni - Molecular imaging, 2010 - journals.sagepub.com
The field of biomedical optics has matured rapidly over the last decade and is poised to
make a significant impact on patient care. In particular, wide-field (typically> 5 cm), planar …

A phase II evaluation of the potent, highly selective PARP inhibitor veliparib in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary …

RL Coleman, MW Sill, K Bell-McGuinn… - Gynecologic …, 2015 - Elsevier
Background Veliparib is a potent small molecule inhibitor of PARP-1/2, which is cytotoxic in
tumor cells with deficiencies in BRCA1 or BRCA2. We studied the clinical activity and toxicity …

[HTML][HTML] Challenges in, and recommendations for, hyperspectral imaging in ex vivo malignant glioma biopsy measurements

A Walke, D Black, PA Valdes, W Stummer, S König… - Scientific reports, 2023 - nature.com
The visualization of protoporphyrin IX (PPIX) fluorescence with the help of surgical
microscopes during 5-aminolevulinic acid-mediated fluorescence-guided resection (FGR) of …

Review of structured light in diffuse optical imaging

JP Angelo, SJ Chen, M Ochoa, U Sunar… - … of biomedical optics, 2019 - spiedigitallibrary.org
Diffuse optical imaging probes deep living tissue enabling structural, functional, metabolic,
and molecular imaging. Recently, due to the availability of spatial light modulators, wide …

Clinical trial of combined radio-and fluorescence-guided sentinel lymph node biopsy in breast cancer

BE Schaafsma, FPR Verbeek… - Journal of British …, 2013 - academic.oup.com
Background Combining radioactive colloids and a near-infrared (NIR) fluorophore permits
preoperative planning and intraoperative localization of deeply located sentinel lymph …

First-in-human pilot study of a spatial frequency domain oxygenation imaging system

S Gioux, A Mazhar, BT Lee, SJ Lin… - … of biomedical optics, 2011 - spiedigitallibrary.org
Oxygenation measurements are widely used in patient care. However, most clinically
available instruments currently consist of contact probes that only provide global monitoring …

Optical technologies for intraoperative neurosurgical guidance

PA Valdes, DW Roberts, FK Lu, A Golby - Neurosurgical focus, 2016 - thejns.org
Biomedical optics is a broadly interdisciplinary field at the interface of optical engineering,
biophysics, computer science, medicine, biology, and chemistry, helping us understand light …

Vision-based navigation in image-guided interventions

DJ Mirota, M Ishii, GD Hager - Annual review of biomedical …, 2011 - annualreviews.org
The trend toward minimally invasive surgical interventions has created new challenges for
visualization during surgical procedures. However, at the same time, the introduction of high …