Clinical proton MR spectroscopy in central nervous system disorders

G Öz, JR Alger, PB Barker, R Bartha, A Bizzi, C Boesch… - Radiology, 2014 - pubs.rsna.org
A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …

A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

Edited magnetic resonance spectroscopy detects an age-related decline in brain GABA levels

F Gao, RAE Edden, M Li, NAJ Puts, G Wang, C Liu… - Neuroimage, 2013 - Elsevier
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain.
Although measurements of GABA levels in vivo in the human brain using edited proton …

MR spectroscopic imaging: principles and recent advances

S Posse, R Otazo, SR Dager… - Journal of Magnetic …, 2013 - Wiley Online Library
MR spectroscopic imaging (MRSI) has become a valuable tool for quantifying metabolic
abnormalities in human brain, prostate, breast and other organs. It is used in routine clinical …

Accelerated MR spectroscopic imaging—a review of current and emerging techniques

W Bogner, R Otazo, A Henning - NMR in Biomedicine, 2021 - Wiley Online Library
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

A subspace approach to high‐resolution spectroscopic imaging

F Lam, ZP Liang - Magnetic resonance in medicine, 2014 - Wiley Online Library
Purpose To accelerate spectroscopic imaging using sparse sampling of‐space and
subspace (or low‐rank) modeling to enable high‐resolution metabolic imaging with good …

Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance …

C Mueller, JC Lin, S Sheriff, AA Maudsley… - Brain imaging and …, 2020 - Springer
Previous neuroimaging studies have detected markers of neuroinflammation in patients with
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Magnetic Resonance …

[HTML][HTML] Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1–13C] pyruvate in vivo

K MacCulloch, A Browning, DOG Bedoya… - Journal of magnetic …, 2023 - Elsevier
Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as
Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to …

[HTML][HTML] GABA and glutamate in schizophrenia: A 7 T 1H-MRS study

A Marsman, RCW Mandl, DWJ Klomp, MM Bohlken… - NeuroImage: Clinical, 2014 - Elsevier
Schizophrenia is characterized by loss of brain volume, which may represent an ongoing
pathophysiological process. This loss of brain volume may be explained by reduced …

High‐resolution 1H‐MRSI of the brain using SPICE: Data acquisition and image reconstruction

F Lam, C Ma, B Clifford, CL Johnson… - Magnetic resonance in …, 2016 - Wiley Online Library
Purpose To develop data acquisition and image reconstruction methods to enable high‐
resolution 1H MR spectroscopic imaging (MRSI) of the brain, using the recently proposed …