Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

Titanium is the second most abundant transition metal and is already a key player in
important industrial processes (eg polyethylene). Titanium is an attractive metal to use for …

Bridged bicyclic scaffolds are emerging bioisosteres of planar aromatic rings under the
concept of “escape from flatland”. However, adopting this concept into the exploration of …

Ketyl radicals are valuable reactive intermediates for synthesis and are used extensively to
construct complex, functionalized products from carbonyl substrates. Single electron transfer …

Low-valent early transition metals are often intrinsically highly reactive as a result of their
strong propensity toward oxidation to more stable high-valent states. Harnessing these …

New catalytic strategies that leverage single-electron redox events have provided chemists
with useful tools for solving synthetic problems. In this context, Ti offers opportunities that are …

Transition‐metal‐catalyzed radical reactions are becoming increasingly important in modern
organic chemistry. They offer fascinating and unconventional ways for connecting molecular …

Described herein is a catalytic asymmetric total synthesis of (−)-actinophyllic acid, with the
key step being a chiral phosphine-catalyzed [3+ 2] annulation between an imine and an …

The asymmetric total syntheses of a group of structurally complex Kopsia alkaloids,(−)‐
kopsine,(−)‐isokopsine,(+)‐methyl chanofruticosinate,(−)‐fruticosine, and (−)‐kopsanone …

The development of Green Chemistry inevitably involves the development of green
reagents. In this review, we highlight that Cp2TiCl is a reagent widely used in radical and …