For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …

Recent advances in targeted therapy and immunotherapy have once again raised the hope
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …

Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

Bacteria are emerging as living drugs to treat a broad range of disease indications.
However, the inherent advantages of these replicating and immunostimulatory therapies …

Antibody fragments for which the sequence is available are suitable for straightforward
engineering and expression in both eukaryotic and prokaryotic systems. When produced as …

Microbial therapy has attracted substantial attention for treating cancers given the advances
in synthetic bioengineering and the characteristics of bacteria in tumor targeting and …

Bacteria have been investigated as anti-tumor therapeutic agents for more than a century,
since Coley first observed successful curing of a patient with inoperable cancer by injection …

The human body is a natural habitat for a multitude of microorganisms, with bacteria being
the major constituent of the microbiota. These bacteria colonize discrete anatomical …

The treatment of some high-incidence human diseases is based on therapeutic cell killing.
In cancer this is mainly achieved by chemical drugs that are systemically administered to …