From therapeutic drug monitoring to model‐informed precision dosing for antibiotics

SG Wicha, AG Märtson, EI Nielsen… - Clinical …, 2021 - Wiley Online Library
Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …

The monitoring of vancomycin: a systematic review and meta-analyses of area under the concentration-time curve-guided dosing and trough-guided dosing

M Tsutsuura, H Moriyama, N Kojima, Y Mizukami… - BMC infectious …, 2021 - Springer
Background This systematic review and meta-analysis explored the relationship between
vancomycin (VCM) monitoring strategies and VCM effectiveness and safety. Methods We …

Evidence-based guideline for therapeutic drug monitoring of vancomycin: 2020 update by the division of therapeutic drug monitoring, Chinese pharmacological …

N He, S Su, Z Ye, G Du, B He, D Li, Y Liu… - Clinical Infectious …, 2020 - academic.oup.com
Background Clinical practice guidelines or recommendations often require timely and
regular updating as new evidence emerges, because this can alter the risk-benefit trade-off …

[HTML][HTML] How to design a study to evaluate therapeutic drug monitoring in infectious diseases?

AG Märtson, MGG Sturkenboom, J Stojanova… - Clinical Microbiology …, 2020 - Elsevier
Background Therapeutic drug monitoring (TDM) is a tool to personalize and optimize dosing
by measuring the drug concentration and subsequently adjusting the dose to reach a target …

Recent advances in therapeutic drug monitoring of voriconazole, mycophenolic acid, and vancomycin: a literature review of pediatric studies

M Resztak, J Sobiak, A Czyrski - Pharmaceutics, 2021 - mdpi.com
The review includes studies dated 2011–2021 presenting the newest information on
voriconazole (VCZ), mycophenolic acid (MPA), and vancomycin (VAN) therapeutic drug …

A moving target—vancomycin therapeutic monitoring

AN Burns, JL Goldman - Journal of the Pediatric Infectious …, 2020 - academic.oup.com
Therapeutic drug monitoring (TDM) has been a common practice to optimize efficacy and
safety of vancomycin. While vancomycin trough-only TDM has widely been integrated into …

Personalised dosing of vancomycin: a prospective and retrospective comparative quasi‐experimental study

L Vali, DR Jenkins, R Vaja… - British journal of clinical …, 2021 - Wiley Online Library
Aims The 2019 update to the US consensus guideline for vancomycin therapeutic
monitoring advocates using Bayesian‐guided personalised dosing to maximise efficacy and …

Time for a Change: Considering Vancomycin Alternatives for Pediatric Methicillin-Resistant Staphylococcus aureus Bacteremia

AS Haynes, H Maples, S Parker - Journal of the Pediatric …, 2023 - academic.oup.com
Vancomycin remains the standard of care for treating methicillin-resistant Staphylococcus
aureus (MRSA) bacteremia in pediatrics largely because no alternative antibiotic is …

Interventions to optimize antimicrobial stewardship

NJ Tinker, RA Foster, BJ Webb, S Haydoura… - Antimicrobial …, 2021 - cambridge.org
Developing and improving an antimicrobial stewardship program successfully requires
evaluation of numerous factors. As technology progresses and our understanding of …

Vancomycin therapeutic drug monitoring in children: new recommendations, similar challenges

JC McNeil, SL Kaplan - The Journal of Pediatric …, 2020 - meridian.allenpress.com
The American Society of Health-System Pharmacists, the Infectious Diseases Society of
America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases …