[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …
Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Hydrogels with tunable stress relaxation regulate stem cell fate and activity
Natural extracellular matrices (ECMs) are viscoelastic and exhibit stress relaxation.
However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically …
However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically …
High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
Elasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targeting
The impact of physical and chemical modifications of nanoparticles on their biological
function has been systemically investigated and exploited to improve their circulation and …
function has been systemically investigated and exploited to improve their circulation and …
Beyond proteases: Basement membrane mechanics and cancer invasion
J Chang, O Chaudhuri - Journal of Cell Biology, 2019 - rupress.org
In epithelial cancers, cells must invade through basement membranes (BMs) to metastasize.
The BM, a thin layer of extracellular matrix underlying epithelial and endothelial tissues, is …
The BM, a thin layer of extracellular matrix underlying epithelial and endothelial tissues, is …
Alginate: properties and biomedical applications
KY Lee, DJ Mooney - Progress in polymer science, 2012 - Elsevier
Alginate is a biomaterial that has found numerous applications in biomedical science and
engineering due to its favorable properties, including biocompatibility and ease of gelation …
engineering due to its favorable properties, including biocompatibility and ease of gelation …
Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair
The objective of this study was to develop an injectable and biocompatible hydrogel which
can efficiently deliver a nanocomplex of graphene oxide (GO) and vascular endothelial …
can efficiently deliver a nanocomplex of graphene oxide (GO) and vascular endothelial …
Tissue cells feel and respond to the stiffness of their substrate
Normal tissue cells are generally not viable when suspended in a fluid and are therefore
said to be anchorage dependent. Such cells must adhere to a solid, but a solid can be as …
said to be anchorage dependent. Such cells must adhere to a solid, but a solid can be as …
The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles
In vitro experiments typically measure the uptake of nanoparticles by exposing cells at the
bottom of a culture plate to a suspension of nanoparticles, and it is generally assumed that …
bottom of a culture plate to a suspension of nanoparticles, and it is generally assumed that …