That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …

Background One of the criteria to objectively prioritize merozoite antigens for malaria
vaccine development is the demonstration that naturally acquired antibodies are associated …

Antibodies play major roles in immunity to malaria; however, a limited understanding of
mechanisms mediating protection is a major barrier to vaccine development. We have …

Individuals living in areas where malaria is endemic are repeatedly exposed to many
different malaria parasite antigens. Studies on naturally acquired antibody-mediated …

Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

The development of effective malaria vaccines may be hindered by extensive genetic
diversity in the surface proteins being employed as vaccine antigens. Understanding of the …

Background Surrogate markers of protective immunity to malaria in humans are needed to
rationalize malaria vaccine discovery and development. In an effort to identify such markers …

Some new cassava accessions have been developed and released because of their high
yield, resistance to disease, adaptability to wider ecological environment, and less cost of …

Background Malaria in pregnancy can expose the fetus to malaria-infected erythrocytes or
their soluble products, thereby stimulating T and B cell immune responses to malaria blood …

Background Plasmodium vivax invasion requires interaction between the human Duffy
antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) …