[HTML][HTML] Epigenetic regulation of the histone-to-protamine transition during spermiogenesis
J Bao, MT Bedford - Reproduction (Cambridge, England), 2016 - ncbi.nlm.nih.gov
In mammals, male germ cells differentiate from haploid round spermatids to flagella-
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
The contribution of human sperm proteins to the development and epigenome of the preimplantation embryo
BACKGROUND Knowledge of the proteomic composition of the gametes is essential to
understand reproductive functions. Most of the sperm proteins are related to …
understand reproductive functions. Most of the sperm proteins are related to …
Identification of proteins involved in human sperm motility using high-throughput differential proteomics
Mammalian sperm motility is a prerequisite for in vivo fertilization, and alterations in this
parameter are commonly observed in infertile males. However, we still do not have a …
parameter are commonly observed in infertile males. However, we still do not have a …
Identification of protein changes in human spermatozoa throughout the cryopreservation process
Cryoinjury is a consequence of cryopreservation and may have a negative impact on sperm
quality regarding motility, morphology, and viability. This study was designed to identify …
quality regarding motility, morphology, and viability. This study was designed to identify …
Insights into the sperm chromatin and implications for male infertility from a protein perspective
Male germ cells undergo an extreme but fascinating process of chromatin remodeling that
begins in the testis during the last phase of spermatogenesis and continues through …
begins in the testis during the last phase of spermatogenesis and continues through …
Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells
LJ Luense, X Wang, SB Schon, AH Weller… - Epigenetics & …, 2016 - Springer
Background During the process of spermatogenesis, male germ cells undergo dramatic
chromatin reorganization, whereby most histones are replaced by protamines, as part of the …
chromatin reorganization, whereby most histones are replaced by protamines, as part of the …
Environmental impact on male (in) fertility via epigenetic route
M Cescon, R Chianese, RS Tavares - Journal of Clinical Medicine, 2020 - mdpi.com
In the last 40 years, male reproductive health—which is very sensitive to both environmental
exposure and metabolic status—has deteriorated and the poor sperm quality observed has …
exposure and metabolic status—has deteriorated and the poor sperm quality observed has …
Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility
J Castillo, JM Estanyol, JL Ballescà… - Asian Journal of …, 2015 - journals.lww.com
The classical idea about the function of the mammalian sperm chromatin is that it serves to
transmit a highly protected and transcriptionally inactive paternal genome, largely …
transmit a highly protected and transcriptionally inactive paternal genome, largely …
Proteomics of human spermatozoa
Proteomic methodologies offer a robust approach to identify and quantify thousands of
proteins from semen components in both fertile donors and infertile patients. These …
proteins from semen components in both fertile donors and infertile patients. These …
High-throughput sperm differential proteomics suggests that epigenetic alterations contribute to failed assisted reproduction
STUDY QUESTION Are there quantitative alterations in the proteome of normozoospermic
sperm samples that are able to complete IVF but whose female partner does not achieve …
sperm samples that are able to complete IVF but whose female partner does not achieve …