The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes
Micronucleus (MN) frequency in cytokinesis-blocked peripheral blood lymphocytes (PBL)
has become one of the best-established biomarkers for studying DNA damage occurring in …
has become one of the best-established biomarkers for studying DNA damage occurring in …
The comet assay as a tool for human biomonitoring studies: the ComNet project
The comet assay is widely used in human biomonitoring to measure DNA damage as a
marker of exposure to genotoxic agents or to investigate genoprotective effects. Studies …
marker of exposure to genotoxic agents or to investigate genoprotective effects. Studies …
Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
Genome editing has therapeutic potential for treating genetic diseases and cancer.
However, the currently most practicable approaches rely on the generation of DNA double …
However, the currently most practicable approaches rely on the generation of DNA double …
Nanoplastics as a potential environmental health factor: effects of polystyrene nanoparticles on human intestinal epithelial Caco-2 cells
C Cortés, J Domenech, M Salazar, S Pastor… - Environmental …, 2020 - pubs.rsc.org
The ubiquitous and increasing presence of micro-/nanoplastics (MNPLs) in our environment
demands an urgent hazard assessment, in order to determine the potential risk they pose to …
demands an urgent hazard assessment, in order to determine the potential risk they pose to …
[HTML][HTML] Investigating landfill leachate toxicity in vitro: A review of cell models and endpoints
D Baderna, F Caloni, E Benfenati - Environment international, 2019 - Elsevier
Landfill leachate is a complex mixture characterized by high toxicity and able to contaminate
soils and waters surrounding the dumpsite, especially in developing countries where …
soils and waters surrounding the dumpsite, especially in developing countries where …
[HTML][HTML] A review of sources, pathways, and toxic effects of human exposure to benzophenone ultraviolet light filters
YN Yao, Y Wang, H Zhang, Y Gao, T Zhang… - Eco-Environment & …, 2024 - Elsevier
Benzophenone ultraviolet light filters (BPs) are high-production-volume chemicals
extensively used in personal care products, leading to widespread human exposure. Given …
extensively used in personal care products, leading to widespread human exposure. Given …
Fate of micronuclei and micronucleated cells
H Hintzsche, U Hemmann, A Poth, D Utesch… - … Research/Reviews in …, 2017 - Elsevier
The present review describes available evidence about the fate of micronuclei and
micronucleated cells. Micronuclei are small, extranuclear chromatin bodies surrounded by a …
micronucleated cells. Micronuclei are small, extranuclear chromatin bodies surrounded by a …
High arsenic in rice is associated with elevated genotoxic effects in humans
Arsenic in drinking water may cause major deleterious health impacts including death.
Although arsenic in rice has recently been demonstrated to be a potential exposure route for …
Although arsenic in rice has recently been demonstrated to be a potential exposure route for …
Chromothripsis: a new mechanism for rapid karyotype evolution
Chromosomal rearrangements are generally thought to accumulate gradually over many
generations. However, DNA sequencing of cancer and congenital disorders uncovered a …
generations. However, DNA sequencing of cancer and congenital disorders uncovered a …
The molecular origins and pathophysiological consequences of micronuclei: New insights into an age-old problem
Micronuclei (MN), the small nucleus-like bodies separated from the primary nucleus, can
exist in cells with numerical and/or structural chromosomal aberrations in apparently normal …
exist in cells with numerical and/or structural chromosomal aberrations in apparently normal …