Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …
various physiological and pathological processes. Their biogenesis involves four key steps …
The ins-and-outs of exosome biogenesis, secretion, and internalization
Exosomes are specialized cargo delivery vesicles secreted from cells by fusion of
multivesicular bodies (MVBs) with the plasma membrane (PM). While the function of …
multivesicular bodies (MVBs) with the plasma membrane (PM). While the function of …
Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance
Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …
most common causes of death worldwide. Since each tumor is unique, there is a need to …
The exosome journey: from biogenesis to uptake and intracellular signalling
S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression
E Yang, X Wang, Z Gong, M Yu, H Wu… - Signal transduction and …, 2020 - nature.com
Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …
Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
Progress in microfluidics‐based exosome separation and detection technologies for diagnostic applications
Exosomes are secreted by most cell types and circulate in body fluids. Recent studies have
revealed that exosomes play a significant role in intercellular communication and are closely …
revealed that exosomes play a significant role in intercellular communication and are closely …
[HTML][HTML] Mechanism and application of exosomes in the wound healing process in diabetes mellitus
D Li, N Wu - Diabetes Research and Clinical Practice, 2022 - Elsevier
Poor wound healing can seriously affect the health of patients with diabetes and result in a
heavy medical burden. Recently, exosomes have been considered the key substances …
heavy medical burden. Recently, exosomes have been considered the key substances …
The emerging role of exosomes in Alzheimer's disease
T Zhang, S Ma, J Lv, X Wang, HK Afewerky, H Li… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), manifested by memory loss and a decline in cognitive
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …
[PDF][PDF] Dysregulated autophagy and lysosome function are linked to exosome production by micro‐RNA 155 in alcoholic liver disease
Cellular homeostais, that is normally maintained through autophagy, is disrupted in
alcoholic liver disease (ALD). Because autophagy and exosome biogenesis share common …
alcoholic liver disease (ALD). Because autophagy and exosome biogenesis share common …