Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management

S Shimony, M Stahl, RM Stone - American Journal of …, 2023 - Wiley Online Library
Disease overview Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell
cancer characterized by unbridled proliferation of malignant marrow stem cells with …

Acute myeloid leukaemia

CD DiNardo, HP Erba, SD Freeman, AH Wei - The Lancet, 2023 - thelancet.com
Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The
past decade has witnessed an increasingly improved scientific understanding of the …

2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party

M Heuser, SD Freeman… - Blood, The Journal …, 2021 - ashpublications.org
Measurable residual disease (MRD) is an important biomarker in acute myeloid leukemia
(AML) that is used for prognostic, predictive, monitoring, and efficacy-response …

Acute myeloid leukemia: current progress and future directions

H Kantarjian, T Kadia, C DiNardo, N Daver… - Blood cancer …, 2021 - nature.com
Progress in the understanding of the biology and therapy of acute myeloid leukemia (AML)
is occurring rapidly. Since 2017, nine agents have been approved for various indications in …

Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed and relapsed or refractory acute myeloid leukemia

CD DiNardo, CA Lachowiez, K Takahashi… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Sixty percent of newly diagnosed patients with acute myeloid leukemia (ND-
AML) receiving frontline therapy attain a complete response (CR), yet 30%-40% of patients …

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia

EJ Duncavage, A Bagg, RP Hasserjian… - Blood, The Journal …, 2022 - ashpublications.org
Myeloid neoplasms and acute leukemias derive from the clonal expansion of hematopoietic
cells driven by somatic gene mutations. Although assessment of morphology plays a crucial …

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

H Döhner, AH Wei, FR Appelbaum… - Blood, The Journal …, 2022 - ashpublications.org
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …

DNA sequencing to detect residual disease in adults with acute myeloid leukemia prior to hematopoietic cell transplant

LW Dillon, G Gui, KM Page, N Ravindra, ZC Wong… - Jama, 2023 - jamanetwork.com
Importance Preventing relapse for adults with acute myeloid leukemia (AML) in first
remission is the most common indication for allogeneic hematopoietic cell transplant. The …

Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach

HM Kantarjian, TM Kadia, CD DiNardo, MA Welch… - Cancer, 2021 - Wiley Online Library
The unraveling of the pathophysiology of acute myeloid leukemia (AML) has resulted in
rapid translation of the information into clinical practice. After more than 40 years of slow …

Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia

CA Lachowiez, N Long, J Saultz, A Gandhi… - Blood …, 2023 - ashpublications.org
Risk stratification in acute myeloid leukemia (AML) remains principle in survival
prognostication and treatment selection. The 2022 European LeukemiaNet (ELN) …