Nano-selenium and its nanomedicine applications: a critical review

B Hosnedlova, M Kepinska, S Skalickova… - International journal …, 2018 - Taylor & Francis
Traditional supplements of selenium generally have a low degree of absorption and
increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of …

Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease

CM Weekley, HH Harris - Chemical Society Reviews, 2013 - pubs.rsc.org
The biological activity of selenium is dependent upon its speciation. We aim to integrate
selenium speciation and metabolism into a discussion of the mechanisms by which …

[HTML][HTML] Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents

E Domínguez-Álvarez, B Rácz, MA Marć… - Drug Resistance …, 2022 - Elsevier
Selenium is an essential trace element that is crucial for cellular antioxidant defense against
reactive oxygen species (ROS). Recently, many selenium-containing compounds have …

FOXO3a in cancer drug resistance

Y Liu, Y Wang, X Li, Y Jia, J Wang, X Ao - Cancer Letters, 2022 - Elsevier
Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

Food sources of selenium and its relationship with chronic diseases

W Hu, C Zhao, H Hu, S Yin - Nutrients, 2021 - mdpi.com
Selenium (Se) is an essential micronutrient for mammals, and its deficiency seriously
threatens human health. A series of biofortification strategies have been developed to …

Protective effects of curcumin against doxorubicin-induced toxicity and resistance: A review

M Mohajeri, A Sahebkar - Critical reviews in oncology/hematology, 2018 - Elsevier
Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

Selenium nanoparticles as a carrier of 5-fluorouracil to achieve anticancer synergism

W Liu, X Li, YS Wong, W Zheng, Y Zhang, W Cao… - ACS …, 2012 - ACS Publications
A simple method for preparing 5-fluorouracil surface-functionalized selenium nanoparticles
(5FU-SeNPs) with enhanced anticancer activity has been demonstrated in the present study …

An update on the mechanisms related to cell death and toxicity of doxorubicin and the protective role of nutrients

A Varela-López, M Battino, MD Navarro-Hortal… - Food and Chemical …, 2019 - Elsevier
Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …

Multifunctional cellular targeting, molecular delivery, and imaging by integrated mesoporous-silica with optical nanocrescent antenna: MONA

Y Park, HJ Yoon, SE Lee, LP Lee - ACS nano, 2022 - ACS Publications
Multifunctional nanoprobes have attracted significant attention in a wide range of disciplines
such as nanomedicine, precision medicine, and cancer diagnosis and treatment. However …

Mechanisms of doxorubicin resistance in hepatocellular carcinoma

J Cox, S Weinman - Hepatic oncology, 2016 - Taylor & Francis
Hepatocellular carcinoma, one of the most common solid tumors worldwide, is poorly
responsive to available chemotherapeutic approaches. While systemic chemotherapy is of …