Poly (ADP-ribose) in the cellular response to DNA damage
NA Berger - Radiation research, 1985 - meridian.allenpress.com
Poly (ADP-ribose) polymerase is a chromatin-bound enzyme which, on activation by DNA
strand breaks, catalyzes the successive transfer of ADP-ribose units from NAD to nuclear …
strand breaks, catalyzes the successive transfer of ADP-ribose units from NAD to nuclear …
Diet, nutrition and telomere length
L Paul - The Journal of nutritional biochemistry, 2011 - Elsevier
The ends of human chromosomes are protected by DNA–protein complexes termed
telomeres, which prevent the chromosomes from fusing with each other and from being …
telomeres, which prevent the chromosomes from fusing with each other and from being …
Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.
IU Schraufstatter, DB Hinshaw… - The Journal of …, 1986 - Am Soc Clin Investig
To determine the biochemical basis of the oxidant-induced injury of cells, we have studied
early changes after exposure of P388D1 murine macrophages to hydrogen peroxide. Total …
early changes after exposure of P388D1 murine macrophages to hydrogen peroxide. Total …
Poly (ADP-Ribose) synthetase. Separation and identification of three proteolytic fragments as the substrate-binding domain, the DNA-binding domain, and the …
I Kameshita, Z Matsuda, T Taniguchi… - Journal of biological …, 1984 - ASBMB
Poly (ADP-ribose) synthetase of Mr= 120,000 is cleaved by limited proteolysis with alpha-
chymotrypsin into two fragments of Mr= 54,000 (54K) and Mr= 66,000 (66K). When the …
chymotrypsin into two fragments of Mr= 54,000 (54K) and Mr= 66,000 (66K). When the …
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.
S Seto, CJ Carrera, M Kubota… - The Journal of …, 1985 - Am Soc Clin Investig
Deoxyadenosine has been implicated as the toxic metabolite causing profound
lymphopenia in immunodeficient children with a genetic deficiency of adenosine deaminase …
lymphopenia in immunodeficient children with a genetic deficiency of adenosine deaminase …
Sulphation of tyrosine residues—a widespread modification of proteins
WB Huttner - Nature, 1982 - nature.com
Of the many known covalent modifications of proteins1, few have been recognized as
widespread. Among these modifications, protein phosphorylation has been extensively …
widespread. Among these modifications, protein phosphorylation has been extensively …
[PDF][PDF] ADP-ribosylation of histone H1
N Ogata - 1980 - repository.kulib.kyoto-u.ac.jp
ADP-ribosylation of Histone H1( Abstract_要旨 ) Page 1 RIGHT: URL: CITATION: AUTHOR(S):
ISSUE DATE: TITLE: ADP-ribosylation of Histone H1( Abstract_要旨 ) Ogata, Norio Ogata …
ISSUE DATE: TITLE: ADP-ribosylation of Histone H1( Abstract_要旨 ) Ogata, Norio Ogata …
Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites
RH Heflich, RE Neft - Mutation Research/Reviews in Genetic Toxicology, 1994 - Elsevier
Acetylaminofluorene and 2-aminofluorene are among the most intensively studied of all
chemical mutagens and carcinogens. Fundamental research findings concerning the …
chemical mutagens and carcinogens. Fundamental research findings concerning the …
DNA strand breaks, NAD metabolism, and programmed cell death
DA Carson, S Seto, DB Wasson, CJ Carrera - Experimental Cell Research, 1986 - Elsevier
An intimate relationship exists between DNA single-strand breaks, NAD metabolism, and
cell viability in quiescent human lymphocytes. Under steady-state conditions, resting …
cell viability in quiescent human lymphocytes. Under steady-state conditions, resting …
Apoptosis overview emphasizing the role of oxidative stress, DNA damage and signal-transduction pathways
CM Payne, C Bernstein, H Bernstein - Leukemia & Lymphoma, 1995 - Taylor & Francis
Apoptosis (programmed cell death) is a central protective response to excess oxidative
damage (especially DNA damage), and is also essential to embryogenesis. morphogenesis …
damage (especially DNA damage), and is also essential to embryogenesis. morphogenesis …