Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

[HTML][HTML] Update from the 2022 World Health Organization classification of thyroid tumors: a standardized diagnostic approach

CK Jung, A Bychkov, K Kakudo - Endocrinology and …, 2022 - synapse.koreamed.org
The fifth edition of the World Health Organization (WHO) histologic classification of thyroid
neoplasms released in 2022 includes newly recognized tumor types, subtypes, and a …

Current practice in patients with differentiated thyroid cancer

M Schlumberger, S Leboulleux - Nature Reviews Endocrinology, 2021 - nature.com
Considerable changes have occurred in the management of differentiated thyroid cancer
(DTC) during the past four decades, based on improved knowledge of the biology of DTC …

Update on fundamental mechanisms of thyroid cancer

A Prete, P Borges de Souza, S Censi… - Frontiers in …, 2020 - frontiersin.org
The incidence of thyroid cancer (TC) has increased worldwide over the past four decades.
TC is divided into three main histological types: differentiated (papillary and follicular TC) …

Thyroid cancer: a review

L Boucai, M Zafereo, ME Cabanillas - Jama, 2024 - jamanetwork.com
Importance Approximately 43 720 new cases of thyroid carcinoma are expected to be
diagnosed in 2023 in the US. Five-year relative survival is approximately 98.5%. This review …

Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma

W Pu, X Shi, P Yu, M Zhang, Z Liu, L Tan, P Han… - Nature …, 2021 - nature.com
The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using
single-cell RNA sequencing, we profile transcriptomes of 158,577 cells from 11 patients' …

NTRK and RET fusion–directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake

YA Lee, H Lee, SW Im, YS Song, DY Oh… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Molecular characterization in pediatric papillary thyroid cancer (PTC),
distinct from adult PTC, is important for developing molecularly targeted therapies for …

Pathogenesis of cancers derived from thyroid follicular cells

JA Fagin, GP Krishnamoorthy, I Landa - Nature reviews Cancer, 2023 - nature.com
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …

[HTML][HTML] DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma

IA González, DR Stewart, KAP Schultz, AP Field… - Modern Pathology, 2022 - Elsevier
Abstract DICER1 syndrome (OMIM 606241, 601200) is a rare autosomal dominant familial
tumor predisposition disorder with a heterozygous DICER1 germline mutation. The most …

Integrative analysis of genomic and transcriptomic characteristics associated with progression of aggressive thyroid cancer

SK Yoo, YS Song, EK Lee, J Hwang, HH Kim… - Nature …, 2019 - nature.com
Anaplastic thyroid cancer (ATC) and advanced differentiated thyroid cancers (DTCs) show
fatal outcomes, unlike DTCs. Here, we demonstrate mutational landscape of 27 ATCs and …