Green chemistry in the synthesis of pharmaceuticals
The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …
Recent advances in the iron‐catalysed multicomponent reactions
S Saranya, T Aneeja, M Neetha… - Applied Organometallic …, 2020 - Wiley Online Library
Iron‐catalysed reactions are widely used in organic synthesis owing to its benefits over other
metals. Among the important organic reactions, multicomponent reactions play a significant …
metals. Among the important organic reactions, multicomponent reactions play a significant …
Asymmetric deoxygenative alkynylation of tertiary amides enabled by iridium/copper bimetallic relay catalysis
Z Li, F Zhao, W Ou, PQ Huang, X Wang - Angewandte Chemie, 2021 - Wiley Online Library
A variety of inert tertiary amides have been successfully transformed into synthetically
important chiral propargylamines in high yields with good to excellent enantioselectivities …
important chiral propargylamines in high yields with good to excellent enantioselectivities …
Enantioselective reductive cyanation and phosphonylation of secondary amides by iridium and chiral thiourea sequential catalysis
DH Chen, WT Sun, CJ Zhu, GS Lu… - Angewandte Chemie …, 2021 - Wiley Online Library
The combination of transition‐metal catalysis and organocatalysis increasingly offers
chemists opportunities to realize diverse unprecedented chemical transformations. By …
chemists opportunities to realize diverse unprecedented chemical transformations. By …
Selective reduction of secondary amides to imines catalysed by Schwartz's reagent
LJ Donnelly, JC Berthet, T Cantat - Angewandte Chemie, 2022 - Wiley Online Library
The partial reduction of amides is a challenging transformation that must overcome the
intrinsic stability of the amide bond and exhibit high chemoselective control to avoid …
intrinsic stability of the amide bond and exhibit high chemoselective control to avoid …
Mild divergent semireductive transformations of secondary and tertiary amides via zirconocene hydride catalysis
RA Kehner, G Zhang… - Journal of the American …, 2023 - ACS Publications
The mild catalytic partial reduction of amides to imines has proven to be a challenging
synthetic transformation, with many transition metals directly reducing these substrates to …
synthetic transformation, with many transition metals directly reducing these substrates to …
Reverse polarity reductive functionalization of tertiary amides via a dual iridium-catalyzed hydrosilylation and single electron transfer strategy
T Rogova, P Gabriel, S Zavitsanou, JA Leitch… - ACS …, 2020 - ACS Publications
A strategy for the mild generation of synthetically valuable α-amino radicals from robust
tertiary amide building blocks has been developed. By combining Vaska's complex …
tertiary amide building blocks has been developed. By combining Vaska's complex …
Uniting Amide Synthesis and Activation by PIII/PV–Catalyzed Serial Condensation: Three-Component Assembly of 2-Amidopyridines
JM Lipshultz, AT Radosevich - Journal of the American Chemical …, 2021 - ACS Publications
An organophosphorus (PIII/PV redox) catalyzed method for the three-component
condensation of amines, carboxylic acids, and pyridine N-oxides to generate 2 …
condensation of amines, carboxylic acids, and pyridine N-oxides to generate 2 …
Homoleptic bis (trimethylsilyl) amides of yttrium complexes catalyzed hydroboration reduction of amides to amines
P Ye, Y Shao, X Ye, F Zhang, R Li, J Sun, B Xu… - Organic …, 2020 - ACS Publications
Homoleptic lanthanide complex Y [N (TMS) 2] 3 is an efficient homogeneous catalyst for the
hydroboration reduction of secondary amides and tertiary amides to corresponding amines …
hydroboration reduction of secondary amides and tertiary amides to corresponding amines …
Concise Total Synthesis of (−)‐Quinocarcin Enabled by Catalytic Enantioselective Reductive 1, 3‐Dipolar Cycloaddition of Secondary Amides
KL Ji, SF He, DD Xu, WX He, JF Zheng… - Angewandte Chemie …, 2023 - Wiley Online Library
A concise asymmetric total synthesis of (−)‐quinocarcin has been accomplished with high
step economy from commercially available starting materials. A catalytic enantioselective …
step economy from commercially available starting materials. A catalytic enantioselective …