Proteoglycans (PGs), molecules in which glycosaminoglycans (GAGs) are covalently linked
to a protein core, are components of the extracellular matrix of all multicellular organisms …

The graded nuclear location of the transcription factor Dorsal along the dorsoventral axis of
the early Drosophila embryo provides positional information for the determination of different …

Introduction 3. Complex structures finely regulated 3.1. The heparan sulfate proteoglycans
3.2. Regulation of chain expression 4. Regulation of cell function 4.1. Human diseases and …

A gradient of Dorsal activity patterns the dorsoventral (DV) axis of the early Drosophila
melanogaster embryo by controlling the expression of genes that delineate presumptive …

The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls
reproductive development and regulates the transcription of steroid-modifying cytochrome …

The pathway that generates the dorsal–ventral (DV) axis of the Drosophila embryo has been
the subject of intense investigation over the previous three decades. The initial asymmetric …

Functional diversification of body parts is dependent on the formation of specialized
structures along the various body axes. In animals, region-specific morphogenesis along the …

Glycan structures are synthesized by a series of reactions conducted by glycosylation‐
related (GR) proteins such as glycosyltransferases, glycan‐modifying enzymes, and …

Drosophila melanogaster embryos develop initially as a syncytium of totipotent nuclei and
subsequently, once cellularized, undergo morphogenetic movements associated with …

Drosophila embryonic dorsal-ventral (DV) polarity is controlled by a group of sequentially
acting serine proteases located in the fluid-filled perivitelline space between the embryonic …