This review gives an overview on the development of research on spider venoms with a
focus on structure and function of venom components and techniques of analysis. Major …

Beyond providing evolutionary advantages, venoms offer unique research tools, as they
were developed to target functionally important proteins and pathways. As a key pain …

The potassium channel Kv1. 3 is an attractive pharmacological target for autoimmune
diseases. Specific peptide inhibitors are key prospects for diagnosing and treating these …

Antimicrobial peptides (AMPs) are components of the innate immune responses that form
the first line of host defense against pathogens. Marine mussels can produce a surprising …

Proteomic analysis of the scorpion venom Scorpio maurus palmatus was performed using
reverse-phase HPLC separation followed by mass spectrometry determination. Sixty five …

Venom is an important genetic development crucial to the survival of scorpions for over
400million years. We studied the evolution of the scorpion venom arsenal by means of …

Scorpion K+ channel toxins and insect defensins share a conserved three-dimensional
structure and related biological activities (defense against competitors or invasive microbes …

cDNA libraries are increasingly being used for high-throughput interrogation of animal
venomes. Most previous studies have focused on discovery of new venom toxins, whereas …

Venomous animals use peptide toxins for hunting and self-defense. To achieve these goals,
toxins need to bind to their targets with high affinity due to the small amount that a single bite …

The lesser Asian scorpion Mesobuthus eupeus (Buthidae) is one of the most widely spread
and dispersed species of the Mesobuthus genus, and its venom is actively studied …