Advancement in leishmaniasis diagnosis and therapeutics: An update

D Kumari, S Perveen, R Sharma, K Singh - European Journal of …, 2021 - Elsevier
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …

[HTML][HTML] Bioactive peptides for anticancer therapies

Y Zhang, C Wang, W Zhang, X Li - Biomaterials Translational, 2023 - ncbi.nlm.nih.gov
Cancer is a serious concern in public health worldwide. Numerous modalities including
surgery, radiotherapy, and chemotherapy, have been used for cancer therapies in clinic …

Biomedical relevance of novel anticancer peptides in the sensitive treatment of cancer

OO Bakare, A Gokul, R Wu, LA Niekerk, A Klein… - Biomolecules, 2021 - mdpi.com
The global increase in cancer mortality and economic losses necessitates the cautious
quest for therapeutic agents with compensatory advantages over conventional therapies …

Neglected zoonotic diseases: Advances in the development of cell-penetrating and antimicrobial peptides against leishmaniosis and Chagas disease

SM Robledo, S Pérez-Silanes, C Fernández-Rubio… - Pathogens, 2023 - mdpi.com
In 2020, the WHO established the road map for neglected tropical diseases 2021–2030,
which aims to control and eradicate 20 diseases, including leishmaniosis and Chagas …

Comparative study of different forms of Jellein antimicrobial peptide on Leishmania parasite

F Zahedifard, H Lee, JH No, M Salimi, N Seyed… - Experimental …, 2020 - Elsevier
Typically, antimicrobial peptides (AMPs) are short positive charged peptides serving a key
role in innate immunity as well as antimicrobial activity. Discovering novel therapeutic …

Bioinformatics analysis for the purpose of designing a novel multi-epitope DNA vaccine against Leishmania major

S Rashidi, SN Faraji, AJ Mamaghani, S Hatam… - Scientific Reports, 2022 - nature.com
Leishmaniasis is one of the main infectious diseases worldwide. In the midst of all the
different forms of the disease, Cutaneous Leishmania (CL) has the highest incidence in the …

Exploring membrane proteins of Leishmania major to design a new multi-epitope vaccine using immunoinformatics approach

M Rabienia, Z Roudbari, A Ghanbariasad… - European Journal of …, 2020 - Elsevier
Leishmaniasis is one of the major global endemic diseases. Among all the different forms of
the disease, cutaneous Leishmaniasis has the highest prevalence worldwide. Treatment …

Systematic review of antiprotozoal potential of antimicrobial peptides

FA Santos, GS Cruz, FA Vieira, BRS Queiroz… - Acta Tropica, 2022 - Elsevier
Protozoa is a group of microorganisms that cause neglected tropical diseases, such as
malaria, Chagas disease, and Leishmaniasis. Due to the growing demand for new …

[HTML][HTML] Lauric acid bilayer-functionalized iron oxide nanoparticles disrupt early development of freshwater snail Biomphalaria glabrata (Say, 1818)

RV Pena, RC Machado, MB Caixeta, PS Araújo… - Acta Tropica, 2022 - Elsevier
Iron oxide nanoparticles (IONPs) have been indicated for the control of parasites and
intermediate hosts, as well as applications in several sectors of nanomedicine. However …

Activity and Cell-Death Pathway in Leishmania infantum Induced by Sugiol: Vectorization Using Yeast Cell Wall Particles Obtained From Saccharomyces cerevisiae

DB Scariot, H Volpato, NS Fernandes… - Frontiers in Cellular …, 2019 - frontiersin.org
Visceral leishmaniasis, caused by Leishmania infantum, is a neglected tropical disease, to
which efforts in the innovation of effective and affordable treatments remain limited, despite …