The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …

Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Prebiotic dietary fibers act as carbon sources for primary and secondary fermentation
pathways in the colon, and support digestive health in many ways. Fructooligosaccharides …

Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …

Objective To highlight the contribution of the gut microbiota to the modulation of host
metabolism by dietary inulin-type fructans (ITF prebiotics) in obese women. Methods A …

Type 2 diabetes is a common metabolic disorder related to insulin resistance, or deficiency
of insulin secretion, caused by decreased insulin sensitivity and destruction of islet structure …

In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased
selectively in adipocytes. Adipose-specific knockout or overexpression of Glut4 alters …

The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …