Most complex human traits differ by sex, but we have limited insight into the underlying
mechanisms. Here, we investigated the influence of biological sex on protein expression …

Sexually dimorphic effects of alcohol, following binge drinking, chronic intoxication, and
withdrawal, are documented at the level of the transcriptome and in behavioral and …

Excessive alcohol use disrupts neuroimmune signaling across various cell types, including
neurons, microglia, and astrocytes. The present review focuses on recent, albeit limited …

The societal implication of sex and gender (SG) differences in brain are profound, as they
influence brain development, behavior, and importantly, the presentation, prevalence, and …

Sex impacts the development of the brain and cognition differently across individuals.
However, the literature on brain sex dimorphism in humans is mixed. We aim to investigate …

Risky alcohol use and alcohol use disorders (AUD) are a rising problem in women, yet a
major disparity in our understanding of what drives alcohol consumption in women remains …

Background Biological factors are known to influence disease trajectories and treatment
effectiveness in alcohol addiction and preclinical and clinical evidence suggests that sex is …

Background Sex differences have been observed in several brain regions for the molecular
mechanisms involved in baseline (resting) and memory-related processes. The ubiquitin …

Introduction The sex difference in alcohol use disorder (AUD) is ingrained in distinctive
neurobiological responses between men and women, which necessitates further …

Somatostatin (SST) is a neuropeptide widely expressed in the central nervous system with
dense expression in limbic regions such as the extended amygdala. It has recently gained …