Applications of Mendelian randomization in psychiatry: a comprehensive systematic review

LF Saccaro, S Gasparini, G Rutigliano - Psychiatric genetics, 2022 - journals.lww.com
Psychiatric diseases exact a heavy socioeconomic toll, and it is particularly difficult to identify
their risk factors and causative mechanisms due to their multifactorial nature, the limited …

Association between testosterone levels and mood disorders: A minireview

S Zito, G Nosari, A Pigoni, C Moltrasio… - Journal of Affective …, 2023 - Elsevier
Background Although many studies reported the neuropsychiatric involvement of
testosterone (T) levels in the development of mood disorders, its role in this disabling …

Causal effect of age at menarche on the risk for depression: results from a two-sample multivariable Mendelian randomization study

R Hirtz, C Hars, R Naaresh, BH Laabs, J Antel… - Frontiers in …, 2022 - frontiersin.org
A fair number of epidemiological studies suggest that age at menarche (AAM) is associated
with depression, but the reported effect sizes are small, and there is evidence of residual …

Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population

R Hirtz, L Libuda, A Hinney, M Föcker… - Journal of Affective …, 2022 - Elsevier
Context The timing of puberty, physical features of pubertal development, and hormones are
closely intertwined but may also individually contribute to the risk for depression and …

Relationship between esophageal squamous cell carcinoma risk and alcohol‐related ALDH2 and ADH1B polymorphisms: Evidence from a meta‐analysis and …

B Zhang, YH Peng, Y Luo, CQ Hong, YW Lin… - Cancer …, 2023 - Wiley Online Library
Background Previous studies have shown that ALDH2 and ADH1B genes may be
associated with alcohol metabolism and the risk of esophageal squamous cell carcinoma …

Depression and generalized anxiety symptoms in idiopathic intracranial hypertension: prevalence, under-reporting and effect on visual outcome

L Donaldson, V Dezard, M Chen, E Margolin - Journal of the Neurological …, 2022 - Elsevier
Background Patients with idiopathic intracranial hypertension (IIH) have been reported to
have high prevalence of co-existent mood disorders. We investigated the frequency of …

Research progress on rheumatoid arthritis-associated depression

N Liu, W Yan, R Su, L Zhang, X Wang, Z Li… - Frontiers in Behavioral …, 2023 - frontiersin.org
Depression is an independent mood disorder and one of the most common comorbidities of
rheumatoid arthritis (RA). Growing evidence suggests that there is two-way regulation …

Depression, higher level of tension induction, and impaired coping strategies in response to stress in women with PCOS correlate with clinical and laboratory indices …

E Dutkiewicz, D Rachoń, M Dziedziak… - Archives of Women's …, 2024 - Springer
PCOS is characterized by ovarian hyperandrogenism and insulin resistance (IR), which give
rise to symptoms of hyperandrogenism and central obesity, which in turn may cause …

The association between testosterone and depression in postmenopausal women: A systematic review of observational studies

C Hemachandra, RM Islam, RJ Bell, F Sultana… - Maturitas, 2023 - Elsevier
Objective The contribution of testosterone to depression in older women is uncertain. This
review was conducted to investigate the association between endogenous testosterone …

Predictive genomic tools in disease stratification and targeted prevention: a recent update in personalized therapy advancements

N Jain, U Nagaich, M Pandey, DK Chellappan, K Dua - EPMA Journal, 2022 - Springer
In the current era of medical revolution, genomic testing has guided the healthcare fraternity
to develop predictive, preventive, and personalized medicine. Predictive screening involves …