Tumors generate physical forces during growth and progression. These physical forces are
able to compress blood and lymphatic vessels, reducing perfusion rates and creating …

Analogies with inert soft condensed matter—such as viscoelastic liquids, pastes, foams,
emulsions, colloids, and polymers—can be used to investigate the mechanical response of …

The stress harbored by the solid phase of tumors is known as solid stress. Solid stress can
be either applied externally by the surrounding normal tissue or induced by the tumor itself …

In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …

During the formation of tissues, cells organize collectively by cell division and apoptosis. The
multicellular dynamics of such systems is influenced by mechanical conditions and can give …

During animal development, several planar cell polarity (PCP) pathways control tissue
shape by coordinating collective cell behavior. Here, we characterize by means of multiscale …

We extend the diffuse interface model developed in Wise et al.(2008) to study nonlinear
tumor growth in 3-D. Extensions include the tracking of multiple viable cell species …

Tumor progression and response to treatment is determined in large part by the generation
of mechanical stresses that stem from both the solid and the fluid phase of the tumor …

In this paper, we develop a thermodynamically consistent four‐species model of tumor
growth on the basis of the continuum theory of mixtures. Unique to this model is the …

Two major mechanisms are involved in the formation of blood vasculature: vasculogenesis
and angiogenesis. The former term describes the formation of a capillary-like network from …