HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta …
RK Gupta, J Gregson, N Parkin… - The Lancet infectious …, 2018 - thelancet.com
Background Pretreatment drug resistance in people initiating or re-initiating antiretroviral
therapy (ART) containing non-nucleoside reverse transcriptase inhibitors (NNRTIs) might …
therapy (ART) containing non-nucleoside reverse transcriptase inhibitors (NNRTIs) might …
HIV-1 drug resistance and resistance testing
DS Clutter, MR Jordan, S Bertagnolio… - Infection, Genetics and …, 2016 - Elsevier
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
HIV infection
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …
virus (HIV), and there are now approximately 37 million individuals living with the infection …
Human immunodeficiency virus drug resistance: 2018 recommendations of the International Antiviral Society–USA Panel
HF Günthard, V Calvez, R Paredes… - Clinical Infectious …, 2019 - academic.oup.com
Background Contemporary antiretroviral therapies (ART) and management strategies have
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …
Effect of HIV-1 low-level viraemia during antiretroviral therapy on treatment outcomes in WHO-guided South African treatment programmes: a multicentre cohort study
LE Hermans, M Moorhouse, S Carmona… - The Lancet infectious …, 2018 - thelancet.com
Background Antiretroviral therapy (ART) that enables suppression of HIV replication has
been successfully rolled out at large scale to HIV-positive patients in low-income and middle …
been successfully rolled out at large scale to HIV-positive patients in low-income and middle …
Current and emerging non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV-1 treatment
Y Wang, E De Clercq, G Li - Expert opinion on drug metabolism & …, 2019 - Taylor & Francis
Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential
components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …
components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …
Optimising HIV pre-exposure prophylaxis and testing strategies in men who have sex with men in Australia, Thailand, and China: a modelling study and cost …
R Zhao, CK Fairley, AR Cook, N Phanuphak… - The Lancet Global …, 2024 - thelancet.com
Background Men who have sex with men (MSM) in the Asia-Pacific region have a
disproportionately high burden of HIV infection compared with the general population …
disproportionately high burden of HIV infection compared with the general population …
Management of virologic failure and HIV drug resistance
SM McCluskey, MJ Siedner… - Infectious Disease Clinics, 2019 - id.theclinics.com
In 2014, the Joint United Nations Programme on HIV and AIDS established global targets
such that 90% of people with HIV will be diagnosed, 90% of those diagnosed will be on …
such that 90% of people with HIV will be diagnosed, 90% of those diagnosed will be on …
Trend of HIV-1 drug resistance in China: a systematic review and meta-analysis of data accumulated over 17 years (2001–2017)
L Zuo, K Liu, H Liu, Y Hu, Z Zhang, J Qin, Q Xu… - …, 2020 - thelancet.com
Background The emergence and spread of HIV-1 drug resistance may compromise HIV
control globally. In response to HIV/AIDS epidemic, China launched national HIV/AIDS …
control globally. In response to HIV/AIDS epidemic, China launched national HIV/AIDS …
Viral reverse transcriptases
L Menéndez-Arias, A Sebastián-Martín, M Álvarez - Virus research, 2017 - Elsevier
Reverse transcriptases (RTs) play a major role in the replication of Retroviridae,
Metaviridae, Pseudoviridae, Hepadnaviridae and Caulimoviridae. RTs are enzymes that are …
Metaviridae, Pseudoviridae, Hepadnaviridae and Caulimoviridae. RTs are enzymes that are …