The synthesis and evaluation of structural analogues and isosteres are of central importance
in medicinal and agricultural chemistry. The sulfonamide functional group represents one of …

Among carbon, hydrogen, oxygen, and nitrogen, sulfur and fluorine are both leading
constituents of the pharmaceuticals that comprise our medicinal history. In efforts to stimulate …

Tubulin inhibitors can interfere with normal cell mitosis and inhibit cell proliferation through
interfering with the normal structure and function of microtubules, forming spindle filaments …

New strategies to access radicals from common feedstock chemicals hold the potential to
broadly impact synthetic chemistry. We report a dual phosphine and photoredox catalytic …

Single electron reduction is more challenging for sulfamoyl chlorides than sulfonyl chlorides.
However, sulfamoyl and sulfonyl chlorides can be easily activated by Cl-atom abstraction by …

This study aimed to isolate and characterize a microbial culture able to degrade
sulfonamides. Sulfamethoxazole (SMX)-degrading microorganisms were enriched from …

A plethora of drug molecules and agrochemicals contain the sulfonamide functional group.
However, sulfonamides are seldom viewed as synthetically useful functional groups. To …

A series of divalent and one trivalent metal chelates of the azo ligand resulting from coupling
of sulfafurazole diazonium chloride with resorcinol have been designed and synthesized …

Sulfonamides are among the most important chemical motifs in pharmaceuticals and
agrochemicals. However, there is no methodology to directly introduce the sulfonamide …

A Ni-catalyzed Negishi cross-coupling with 1, 1-disubstituted styrenyl aziridines has been
developed. This method delivers valuable β-substituted phenethylamines via a challenging …