Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

Insight into the motion of water conveying three kinds of nanoparticles shapes on a horizontal surface: significance of thermo-migration and Brownian motion

S Saleem, IL Animasaun, SJ Yook, QM Al-Mdallal… - Surfaces and …, 2022 - Elsevier
Thermo-migration and erratic/random motion of tiny particles are some of the attributes of
these objects in liquid medium that can affect the performance and transportation of …

Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment

Z Li, Y Ding, J Liu, J Wang, F Mo, Y Wang… - Nature …, 2022 - nature.com
Immunosuppressive cells residing in the tumor microenvironment, especially tumor
associated macrophages (TAMs), hinder the infiltration and activation of T cells, limiting the …

Degradable gelatin-based IPN cryogel hemostat for rapidly stopping deep noncompressible hemorrhage and simultaneously improving wound healing

Y Huang, X Zhao, Z Zhang, Y Liang, Z Yin… - Chemistry of …, 2020 - ACS Publications
Biodegradable cryogel wound dressing which can stop deep noncompressible hemorrhage
and simultaneously promote wound healing is a highly promising biomaterial in clinics …

Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Emerging hemostatic materials for non-compressible hemorrhage control

R Dong, H Zhang, B Guo - National Science Review, 2022 - academic.oup.com
Non-compressible hemorrhage control is a big challenge in both civilian life and the
battlefield, causing a majority of deaths among all traumatic injury mortalities. Unexpected …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Nanoparticle biointerfacing by platelet membrane cloaking

CMJ Hu, RH Fang, KC Wang, BT Luk… - Nature, 2015 - nature.com
Abstract Development of functional nanoparticles can be encumbered by unanticipated
material properties and biological events, which can affect nanoparticle effectiveness in …

Biomaterials and advanced technologies for hemostatic management of bleeding

DSA Hickman, CL Pawlowski, UDS Sekhon… - Advanced …, 2018 - Wiley Online Library
Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …