Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectives

S Datta, D Aggarwal, N Sehrawat, M Yadav, V Sharma… - Phytomedicine, 2023 - Elsevier
Background: The liver is a well-known player in the metabolism and removal of drugs. Drug
metabolizing enzymes in the liver detoxify drugs and xenobiotics, ultimately leading to the …

Hallmarks of the human intestinal microbiome on liver maturation and function

JI Almeida, MF Tenreiro, L Martinez-Santamaria… - Journal of …, 2022 - Elsevier
As one of the most metabolically complex systems in the body, the liver ensures multi-organ
homeostasis and ultimately sustains life. Nevertheless, during early postnatal development …

The antioxidant and anti-inflammatory effects of Carica Papaya Linn. seeds extract on CCl4-induced liver injury in male rats

NZ Shaban, SM El-Kot, OM Awad, AM Hafez… - … Medicine and Therapies, 2021 - Springer
Background Oxidative stress (OS) and inflammation are the central pathogenic events in
liver diseases. In this study, the protective and therapeutic role of Carica Papaya Linn. seeds …

[HTML][HTML] Protective mechanism of Coprinus comatus polysaccharide on acute alcoholic liver injury in mice, the metabolomics and gut microbiota investigation

J Yu, J Sun, M Sun, W Li, D Qi, Y Zhang… - Food Science and Human …, 2024 - Elsevier
Coprinus comatus polysaccharide (CCP) has significant hepatoprotective effect. To explore
hepatoprotective mechanism of CCP, the study analyzed preventive effect of CCP on acute …

LC-MS/MS and GC-MS Analysis for the Identification of Bioactive Metabolites Responsible for the Antioxidant and Antibacterial Activities of Lygodium microphyllum …

WY Teoh, YS Yong, FN Razali, S Stephenie… - Separations, 2023 - mdpi.com
Natural products serve as a valuable source of antioxidants with potential health benefits for
various conditions. Lygodium microphyllum (Cav.) R. Br., also known as Old World climbing …

Curative role of pantothenic acid in brain damage of gamma irradiated rats

S Sm, S Hn, E Na, H As - Indian Journal of Clinical Biochemistry, 2018 - Springer
Radiation induced brain damage is associated with impairment of mitochondrial functions,
variations in the level of neurotransmitters, and oxidative stress. Mitochondrial function is …

Anti‐inflammatory activity of ginger modulates macrophage activation against the inflammatory pathway of monosodium glutamate

M Abd El Hady Mousa, H Mansour… - Journal of Food …, 2021 - Wiley Online Library
Monosodium glutamate (MSG) has been traditionally used as a flavor enhancer and is
added to many foods. The chronic consumption of MSG has been suggested as causing …

Alisma plantago-aquatica polysaccharides ameliorate acetaminophen-induced acute liver injury by regulating hepatic metabolic profiles and modulating gut …

P Lei, X Li, L Jiang, H Yu, P Zhang, L Han… - International Journal of …, 2024 - Elsevier
Acetaminophen (APAP) has emerged as a predominant contributor to acute liver failure
(ALF) in United States. Alismatis rhizoma, a commonly used traditional herbal medicine …

Antioxidant potency of n-butanol fraction of Ficus glumosa leaves against oxidative stress induced by carbon tetrachloride in the kidneys of rats

MSABU ABU, OE YAKUBU, JOBI ONUCHE… - Nusantara …, 2022 - smujo.id
Abu MS, Yakubu OE, Onuche JI, Tatah SV. 2022. Antioxidant potency of n-butanol fraction
on Ficus glumosa leaves against oxidative stress induced by carbon tetrachloride in the …

Shizao decoction for cirrhotic ascites: assessing potential targets based on network analysis combined with pharmacokinetics and metabolomics

W Li, Y Hou, Y Wang, R Liu, H Zhang, Y Luo… - Frontiers in …, 2024 - frontiersin.org
Introduction: Shizao decoction (SZD) is a traditional Chinese medicine decoction that has
therapeutic effects on cirrhotic ascites (CAS). Because of the unclear treatment mechanism …