Clostridium difficile infection
J Czepiel, M Dróżdż, H Pituch, EJ Kuijper… - European Journal of …, 2019 - Springer
Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …
is widely distributed in the intestinal tract of humans and animals and in the environment. In …
Clostridium difficile infection
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …
threatening, especially in elderly people and in patients who have dysbiosis of the gut …
The role of toxins in Clostridium difficile infection
R Chandrasekaran, DB Lacy - FEMS microbiology reviews, 2017 - academic.oup.com
Clostridium difficile is a bacterial pathogen that is the leading cause of nosocomial antibiotic-
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …
Clostridium difficile Toxin Biology
K Aktories, C Schwan, T Jank - Annual review of microbiology, 2017 - annualreviews.org
Clostridium difficile is the cause of antibiotics-associated diarrhea and pseudomembranous
colitis. The pathogen produces three protein toxins: C. difficile toxins A (TcdA) and B (TcdB) …
colitis. The pathogen produces three protein toxins: C. difficile toxins A (TcdA) and B (TcdB) …
Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal Effects
S Di Bella, P Ascenzi, S Siarakas, N Petrosillo… - Toxins, 2016 - mdpi.com
Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …
An overview of healthcare associated infections and their detection methods caused by pathogen bacteria in Romania and Europe
Healthcare-associated infections can occur in different care units and can affect both
patients and healthcare professionals. Bacteria represent the most common cause of …
patients and healthcare professionals. Bacteria represent the most common cause of …
Clostridium difficile Toxins: Mechanism of Action and Role in Disease
DE Voth, JD Ballard - Clinical microbiology reviews, 2005 - Am Soc Microbiol
As the leading cause of hospital-acquired diarrhea, Clostridium difficile colonizes the large
bowel of patients undergoing antibiotic therapy and produces two toxins, which cause …
bowel of patients undergoing antibiotic therapy and produces two toxins, which cause …
Animal models to study acute and chronic intestinal inflammation in mammals
JA Jiminez, TC Uwiera, G Douglas Inglis, RRE Uwiera - Gut pathogens, 2015 - Springer
Acute and chronic inflammatory diseases of the intestine impart a significant and negative
impact on the health and well-being of human and non-human mammalian animals …
impact on the health and well-being of human and non-human mammalian animals …
Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during Clostridium difficile infections
Clostridium difficile is a leading cause of antibiotic-associated diarrhea, a significant animal
pathogen, and a worldwide public health burden. Most disease-causing strains secrete two …
pathogen, and a worldwide public health burden. Most disease-causing strains secrete two …
Isothiocyanates: An overview of their antimicrobial activity against human infections
L Romeo, R Iori, P Rollin, P Bramanti, E Mazzon - Molecules, 2018 - mdpi.com
The use of plant-derived products as antimicrobial agents has been investigated in depth.
Isothiocyanates (ITCs) are bioactive products resulting from enzymatic hydrolysis of …
Isothiocyanates (ITCs) are bioactive products resulting from enzymatic hydrolysis of …