Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19

M Cutolo, V Smith, S Paolino, E Gotelli - Nature Reviews Rheumatology, 2023 - nature.com
Evidence supporting the extra-skeletal role of vitamin D in modulating immune responses is
centred on the effects of its final metabolite, 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3, also …

Rapidly Increasing Serum 25 (OH) D Boosts the Immune System, against Infections—Sepsis and COVID-19

SJ Wimalawansa - Nutrients, 2022 - mdpi.com
Vitamin D deficiency is a global public health problem, a pandemic that commonly affects
the elderly and those with comorbidities such as obesity, diabetes, hypertension, respiratory …

Vitamin D supplementation for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials

LS Kümmel, H Krumbein, PC Fragkou… - Frontiers in …, 2022 - frontiersin.org
Vitamin D supplementation and its impact on immunoregulation are widely investigated. We
aimed to assess the prevention and treatment efficiency of vitamin D supplementation in the …

Vitamin D supplementation and clinical outcomes in severe COVID-19 patients—randomized controlled trial

J Domazet Bugarin, S Dosenovic, D Ilic, N Delic, I Saric… - Nutrients, 2023 - mdpi.com
COVID-19 symptoms vary from asymptomatic cases to moderate and severe illness with
patients needing hospitalization and intensive care treatment. Vitamin D is associated with …

The effect of vitamin D supplementation on the length of hospitalisation, intensive care unit admission, and mortality in COVID-19—A systematic review and meta …

AC Sîrbu, O Sabin, IC Bocșan, ȘC Vesa, AD Buzoianu - Nutrients, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic caused by the Severe Acute
Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has become a global health crisis and …

Vitamin D supplementation and COVID-19 outcomes: mounting evidence and fewer doubts

AFG Cicero, F Fogacci, C Borghi - Nutrients, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) has already killed more than 6 million people
around the world. A growing body of epidemiological evidence suggests that low 25-hydroxy …

Vitamin D and COVID-19: narrative review after 3 Years of pandemic

E Gotelli, S Soldano, E Hysa, S Paolino, R Campitiello… - Nutrients, 2022 - mdpi.com
Active vitamin D [1, 25 (OH) 2D3—calcitriol] is a secosteroid hormone whose receptor is
expressed on all cells of the immune system. Vitamin D has a global anti-inflammatory effect …

Overcoming infections including COVID-19, by maintaining circulating 25 (OH) D concentrations above 50 ng/mL

SJ Wimalawansa - Pathology and Laboratory Medicine …, 2022 - Taylor & Francis
The elderly and those with underlying chronic diseases (ie, comorbidities) such as
pulmonary, cardiovascular, metabolic, and renal diseases, increase their susceptibility to …

The impact of supplementing vitamin D through different methods on the prognosis of COVID-19 patients: a systematic review and meta-analysis

X Zhang, J Wu, H Dong, N Shang, Y Li, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Objective To analyze the impact of different methods of Vitamin D administration on the
prognosis of COVID-19 patients. Methods A comprehensive literature search was conducted …