Brain borders at the central stage of neuroimmunology
J Rustenhoven, J Kipnis - Nature, 2022 - nature.com
The concept of immune privilege suggests that the central nervous system is isolated from
the immune system. However, recent studies have highlighted the borders of the central …
the immune system. However, recent studies have highlighted the borders of the central …
Cytokines as emerging regulators of central nervous system synapses
Cytokines are key messengers by which immune cells communicate, and they drive many
physiological processes, including immune and inflammatory responses. Early discoveries …
physiological processes, including immune and inflammatory responses. Early discoveries …
Role of regulatory non-coding RNAs in traumatic brain injury
Traumatic brain injury (TBI) is a potentially fatal health event that cannot be predicted in
advance. After TBI occurs, it can have enduring consequences within both familial and …
advance. After TBI occurs, it can have enduring consequences within both familial and …
Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study
O Aousji, S Feldengut, S Antonucci, M Schön… - Acta Neuropathologica …, 2023 - Springer
Abstract Amyotrophic Lateral Sclerosis (ALS) is mainly characterized by the degeneration of
corticospinal neurons and spinal α-motoneurons; vulnerable cells display prominent pTDP …
corticospinal neurons and spinal α-motoneurons; vulnerable cells display prominent pTDP …
Type 2 immunity in the brain and brain borders
T Mamuladze, J Kipnis - Cellular & Molecular Immunology, 2023 - nature.com
Recent research in neuroimmunology has revolutionized our understanding of the intricate
interactions between the immune system and the central nervous system (CNS). The CNS …
interactions between the immune system and the central nervous system (CNS). The CNS …
[HTML][HTML] Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex
C Koupourtidou, V Schwarz, H Aliee, S Frerich… - Nature …, 2024 - nature.com
Traumatic brain injury leads to a highly orchestrated immune-and glial cell response
partially responsible for long-lasting disability and the development of secondary …
partially responsible for long-lasting disability and the development of secondary …
Targeting pyroptosis with nanoparticles to alleviate neuroinflammatory for preventing secondary damage following traumatic brain injury
X Zhang, X Huang, D Hang, J Jin, S Li, Y Zhu… - Science Advances, 2024 - science.org
Posttraumatic neuroinflammation is a key driver of secondary injury after traumatic brain
injury (TBI). Pyroptosis, a proinflammatory form of programmed cell death, considerably …
injury (TBI). Pyroptosis, a proinflammatory form of programmed cell death, considerably …
Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior
The innate immune system shapes brain development and is implicated in
neurodevelopmental diseases. It is critical to define the relevant immune cells and signals …
neurodevelopmental diseases. It is critical to define the relevant immune cells and signals …
Analytically controlling the laser-induced electron phase in sub-cycle motion
We develop an approach to directly control the phase of an electron's sub-cycle motion in an
intense laser field. The method is established by tuning a low-frequency electric field applied …
intense laser field. The method is established by tuning a low-frequency electric field applied …
Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model
F Olde Heuvel, N Ouali Alami, O Aousji… - Molecular Autism, 2023 - Springer
Abstract Background Autism Spectrum Disorders (ASD) patients experience disturbed
nociception in the form of either hyposensitivity to pain or allodynia. A substantial amount of …
nociception in the form of either hyposensitivity to pain or allodynia. A substantial amount of …