Fabry disease is an X-linked lysosomal storage disorder due to deficiency of the enzyme α-
galactosidase A. The principal clinical manifestations of Fabry disease consist of …

Characteristic clinical manifestations of AFD such as acroparesthesias, angiokeratoma,
corneal opacity, hypo/and anhidrosis, gastrointestinal symptoms, renal and cardiac …

Mechanical testing and modelling of a material for biomedical applications have to be based
on conditions representative of the application of interest. In this work, an ether-based …

BACKGROUND: Cardiac involvement is responsible for substantial morbidity and mortality
in Anderson–Fabry disease (AFD). We sought to document its onset and progression in a …

Over the past three decades, enzyme therapy for lysosomal storage diseases has moved
from an academic pursuit to direct delivery of effective clinical care for affected patients and …

The renin-angiotensin system (RAS) is a hormonal system that controls body fluid volume,
blood pressure, and cardiovascular function in both health and disease. Various tissues …

Fabry disease (McKusick 301500) is an X-linked lysosomal storage disorder due to deficient
α-galactosidase A activity, which leads to accumulation of glycosphingolipids, especially in …

Purpose To test the hypothesis that reactive oxygen species contribute to the cerebral
hyperperfusion in Fabry disease. Material and Methods We examined the effect of …

Objective: Fabry disease is a lysosomal storage disorder due to deficient α-galactosidase A
activity, which leads to glycosphingolipid accumulation especially in vascular smooth …

Circulating tumor cells (CTCs) have been reported to correlate most closely with cancer
development, and can serve as an important marker for metastatic malignancy, tumor …